Locomotion of Autistic Adults

Hallett, Mark; Lebiedowska, Maria K.; Thomas, Sarah M.; Stanhope, Steven J.; Denckla, Martha B.; Rumsey, Judith M.

doi:10.1001/archneur.1993.00540120019007

Cited by 184 publications

(129 citation statements)

References 9 publications

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“…A sophisticated biomechanical assessment of five adults with autism and five healthy controls (Hallett et al 1993) did not replicate the gait abnormality findings of Vilensky et al (1981). The only significant difference found between the groups was decreased range of ankle motion.…”

Section: Introductionmentioning

confidence: 76%

Gross Motor Development, Movement Abnormalities, and Early Identification of Autism

Ozonoff

Young

Goldring

et al. 2007

J Autism Dev Disord

269

189

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Gross motor development (supine, prone, rolling, sitting, crawling, walking) and movement abnormalities were examined in the home videos of infants later diagnosed with autism (regression and no regression subgroups), developmental delays (DD), or typical development. Group differences in maturity were found for walking, prone, and supine, with the DD and © Springer Scicnce+Business Media, LLC 2007 Correspondence to: Sally Ozonoff, sjo7.onoff@ucdavis.edu. HHS Public Access Author Manuscript Author ManuscriptAuthor Manuscript Author ManuscriptAutism-No Regression groups both showing later developing motor maturity than typical children. The only statistically significant differences in movement abnormalities were in the DD group; the two autism groups did not differ from the typical group in rates of movement abnormalities or lack of protective responses. These findings do not replicate previous investigations suggesting that early motor abnormalities seen on home video can assist in early identification of autism.

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Section: Introductionmentioning

confidence: 76%

Gross Motor Development, Movement Abnormalities, and Early Identification of Autism

Ozonoff

Young

Goldring

et al. 2007

J Autism Dev Disord

269

189

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“…A study showed that typical stereotypies observed in autistic patients cannot be certainly distinguished from dyskinesis. 103 This finding draws attention to the importance of characterizing and quantifying abnormal movements before prescribing medications.…”

Section: Therapeutic Interventionsmentioning

confidence: 97%

Autismo e doenças invasivas de desenvolvimento

Gadia¹,

Tuchman²,

Rotta³

2004

J. Pediatr. (Rio J.)

119

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Objective: To review the current knowledge on neurobiological aspects of autism and pervasive developmental disorders, as well as to provide pediatricians with up to date information on diagnosis and treatment of autism. Sources of data: Review of MEDLINE and Internet.Summary of the findings: Autism is the 3rd developmental disorder, with an incidence of 40 to 130/100,000 individuals. Diagnosis is based on clinical findings, following DSM IV criteria. Neuroimaging, investigation of fetal neurological status, and genetic investigation contribute towards a better understanding of the neurobiology of autism. Conclusion:Pediatricians are the first health professional to come in contact with patients with autism. Thus, they should be able to diagnose and to coordinate the multidisciplinary treatment of these patients.J Pediatr (Rio J). 2004;80(2 Suppl):S83-S94: Autism, child behavior, child development.

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“…Some of these characteristics pertain to additional impairments. For example, motor-related deficits have been identified in ASD, relating to a variety of aspects, such as dexterity (Ghaziuddin and Butler 1998), planning (Mari et al 2003;Schmitz et al 2003), posture (Minshew et al 2004), gait (Hallett et al 1993), and learning (Mostofsky et al 2000). This catalogue implies that many parts of the motor networks may be affected, including premotor cortices, cerebellum, and basal ganglia.…”

Section: Behaviormentioning

confidence: 99%

The study of autism as a distributed disorder

Müller

2007

Ment. Retard. Dev. Disabil. Res. Rev.

173

135

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Past autism research has often been dedicated to tracing the causes of the disorder to a localized neurological abnormality, a single functional network, or a single cognitive-behavioral domain. In this review, I argue that autism is a 'distributed disorder' on various levels of study (genetic, neuroanatomical, neurofunctional, behavioral). 'Localizing' models are therefore not promising. The large array of potential genetic risk factors suggests that multiple (or all) emerging functional brain networks are affected during early development. This is supported by widespread growth abnormalities throughout the brain. Interactions during development between affected functional networks and atypical experiential effects (associated with atypical behavior) in children with autism further complicate the neurological bases of the disorder, resulting in an 'exponentially distributed' profile. Promising approaches to a better characterization of neural endophenotypes in autism are provided by techniques investigating white matter and connectivity, such as MR spectroscopy, diffusion tensor imaging (DTI), and functional connectivity MRI. According to a recent hypothesis, the autistic brain is generally characterized by 'underconnectivity'. However, not all findings are consistent with this view. The concepts and methodology of functional connectivity need to be refined and results need to be corroborated by anatomical studies (such as DTI tractography) before definitive conclusions can be drawn.

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Locomotion of Autistic Adults

Cited by 184 publications

References 9 publications

Gross Motor Development, Movement Abnormalities, and Early Identification of Autism

Gross Motor Development, Movement Abnormalities, and Early Identification of Autism

Autismo e doenças invasivas de desenvolvimento

The study of autism as a distributed disorder

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