Localized Vocal Cord Amyloidosis

Abstract

Localized laryngeal amyloidosis is an uncommon diease with limited long-term followup studies. The precise etiology and pathogenesis are not entirely clear. We present a case of localized laryngeal amyloidosis. 35 years old man suffered from hoarseness during the last six months. Laryngoscopic examination showed nodular infiltration of bilateral vocal cords. Amyloidosis was confirmed by the characteristic Congo red staining of biopsies. The search for other localizations of amyloidosis was negative. No evidence of systemic amyloidosis or plasma cell proliferation was found in this patient. There were no recurrences during the nine-months follow-up.