Localized surface plasmon resonance properties and biomedical applications of copper selenide nanomaterials

Ai, Kelong; Huang, Jia; Xiao, Zhu; Yang, Yan‐Ru; Bai, Yanru; Peng, Jianhui

doi:10.1016/j.mtchem.2020.100402

Cited by 44 publications

(34 citation statements)

References 119 publications

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“…With the development of nanotechnology, plenty of nanoscale drug delivery systems (DDSs) have been applied to the chemotherapy drug delivery, such as micelles, vesicles, nanogels, and dendrimer (Gu et al, 2015;Li et al, 2018;Chen et al, 2020;Su et al, 2020). Among them, the polymer nanoparticles were possibly the most promising (Choi et al, 2012;Wang et al, 2012;Ai et al, 2021). Through special design, nanoparticles could achieve specific functions, such as increasing the solubility of chemotherapy drugs and improving the stability in circulation (Cherukuri and Curley, 2010;Laroui et al, 2011).…”

Section: Introductionmentioning

confidence: 99%

Doxorubicin-Loaded Tumor-Targeting Peptide-Decorated Polypeptide Nanoparticles for Treating Primary Orthotopic Colon Cancer

Liu

Wang

et al. 2021

Front. Pharmacol.

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Colorectal cancer is the third most common malignant disease worldwide, and chemotherapy has been the standard treatment for colorectal cancer. However, the therapeutic effects of chemotherapy are unsatisfactory for advanced and recurrent colorectal cancers. Thus, increasing the treatment efficacy of chemotherapy in colorectal cancer is a must. In this study, doxorubicin (DOX)-loaded tumor-targeting peptide-decorated mPEG-P(Phe-co-Cys) nanoparticles were developed to treat orthotopic colon cancer in mice. The peptide VATANST (STP) can specifically bind with vimentin highly expressed on the surface of colon cancer cells, thus achieving the tumor-targeting effects. The nanoparticles are core-shell structured, which can protect the loaded DOX while passing through the blood flow and increase the circulation time. The disulfide bonds within the nanoparticles are sensitive to the glutathione-rich microenvironment of tumor tissues. Rupture of disulfide bonds of the nanoparticles leads to the continuous release of DOX, thus resulting in the apoptosis of the tumor cells. The in vivo experiments in mice with orthotopic colon cancer demonstrated that the synthesized DOX-loaded tumor-targeting peptide-decorated polypeptide nanoparticles showed properties of drug delivery systems and exhibited good antitumor properties. The synthesized nanoparticles show appropriate properties as one of the drug delivery systems and exhibit good antitumor properties after encapsulating DOX.

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Section: Introductionmentioning

confidence: 99%

Doxorubicin-Loaded Tumor-Targeting Peptide-Decorated Polypeptide Nanoparticles for Treating Primary Orthotopic Colon Cancer

Liu

Wang

et al. 2021

Front. Pharmacol.

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“…The emergence of nanoplatforms has enabled more and more novel nanomaterials to be delivered to tumor tissues to accomplish radiosensitization while reducing systemic toxicity, as a result of the integration of nanotechnology in the area of cancer treatment ( 13 ). MoS 2 -based nanomaterials and copper selenide nanomaterials have been explored to realize radiosensitization ( 14 , 15 ). These studies provide new insights for the selection of radiotherapy sensitizers.…”

Section: Introductionmentioning

confidence: 99%

Platelet Membranes Coated Gold Nanocages for Tumor Targeted Drug Delivery and Amplificated Low-Dose Radiotherapy

et al. 2021

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Continuous high doses of radiation can cause irreversible side effects and radiation resistance; thus, advanced radiosensitizers are urgently needed. To overcome this problem, we developed a nano platelet radiosensitization system (PCA) by coating the chemotherapeutic drug cisplatin (CDDP) loaded gold nanocages (AuNs) within the platelet membrane. The developed PCA system may enable AuNs to have immune escape and targeting capabilities. After administration, PCA will actively target tumor cells and avoid being cleared by the immune system. Subsequently, CDDP, which destroys tumor cell DNA, can not only kill tumor cells directly but also combine with AuNs, which deposit radiation energy into tumor tissues, reducing RT resistance. In vivo and in vitro studies revealed that the combination of PCA with RT (2Gy) efficiently inhibits tumor proliferation without causing side effects such as inflammation. To conclude, this is the first attempt to use platelet membranes to correctly transport AuNs while also accomplishing low-dose RT, which could help AuNs-based tumor RT become more effective.

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“…The targeted development of cancer treatment technology-including chemotherapy, radiotherapy, and immunotherapy-has enormous potential in tumor treatment, although most such technologies are yet to be used routinely in the clinic (1)(2)(3)(4)(5). Among therapeutic approaches being developed, treating cancer with CO gas is both novel and practical, yet remains underexplored.…”

Section: Introductionmentioning

confidence: 99%

A Novel H2O2 Generator for Tumor Chemotherapy-Enhanced CO Gas Therapy

Liu

Zeng

et al. 2021

Front. Oncol.

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Carbon monoxide (CO) gas therapy is a promising cancer treatment. However, gas delivery to the tumor site remains problematic. Proper tunable control of CO release in tumors is crucial to increasing the efficiency of CO treatment and reducing the risk of CO poisoning. To overcome such challenges, we designed ZCM, a novel stable nanotechnology delivery system comprising manganese carbonyl (MnCO) combined with anticancer drug camptothecin (CPT) loaded onto a zeolitic imidazole framework-8 (ZIF-8). After intravenous injection, ZCM gradually accumulates in cancerous tissues, decomposing in the acidic tumor microenvironment, releasing CPT and MnCO. CPT acts as a chemotherapy agent destroying tumors and producing copious H2O2. MnCO can react with the H2O2 to generate CO, powerfully damaging the tumor. Both in vitro and in vivo experiments indicate that the ZCM system is both safe and has excellent tumor inhibition properties. ZCM is a novel system for CO controlled release, with significant potential to improve future cancer therapy.

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Localized surface plasmon resonance properties and biomedical applications of copper selenide nanomaterials

Cited by 44 publications

References 119 publications

Doxorubicin-Loaded Tumor-Targeting Peptide-Decorated Polypeptide Nanoparticles for Treating Primary Orthotopic Colon Cancer

Doxorubicin-Loaded Tumor-Targeting Peptide-Decorated Polypeptide Nanoparticles for Treating Primary Orthotopic Colon Cancer

Platelet Membranes Coated Gold Nanocages for Tumor Targeted Drug Delivery and Amplificated Low-Dose Radiotherapy

A Novel H2O2 Generator for Tumor Chemotherapy-Enhanced CO Gas Therapy

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