Localized scleroderma causing enophthalmos: A rare entity

The role of fibroblasts in the pathogenesis of linear morphoea: targeting the secretome

“…In severe clinical manifestations of the disorder, involvement of the underlying musculoskeletal structures can cause muscle atrophy, joint contractures, limb length discrepancies and irreversible structural deformities . A recent report has also described the complication of enophthalmos in an individual with the disease . Although the causes of LM are likely multifactorial, the lesions present typically along the lines of Blaschko, indicative of the pathology being of embryonic origin, with genetic mosaicism …”