Localized Manipulation of Magnetic Particles in an Ensemble

See, Hian Hian; Herath, Sahan C. B.; Du, Yuanmin; Asada, H. Harry; Chen, Peter C. Y.

doi:10.1109/access.2018.2829715

Cited by 6 publications

(6 citation statements)

References 35 publications

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“…All the other manipulation setups are designed to work with objects at least 20 times bigger. The experiments reported in [20], [29], [30], [39], and [33] exhibit a population limited to 3 particles distanced at few millimeters and the scaling comes at a great cost in control accuracy and selectivity. In [35], a population of 6 particles is reported.…”

Section: Discussion a Performance Analysismentioning

confidence: 99%

“…Even if all these manipulation setups allow to manipulate single particles, their selectivity is poor because of the utilization of global magnetic fields. Only [20] demonstrates true selective manipulation but it requires the particles to be outside the radius of influence of the magnetic source which is around 500 µm. The selectivity reported in [35] is limited due to Trajectories are in blue for particle 1 and in red for particle 2.…”

Section: Discussion a Performance Analysismentioning

confidence: 99%

“…Manipulation using magnetic fields has found a wide range of applications such as sorting and trapping of magnetically tagged micro-organisms [12], [13], sub-cellular control of signaling [14] and immunoassays [15], to name a few. A variety of techniques have been developed where the magnetic field is generated by external sources such as permanent magnet [16], electromagnets [17], Helmholtz coils [18] static [19], [20] and dynamic electromagnetic needles [21] or micro-patterned current wires in microfluidic chips [22]. The applied magnetic field can be global, i.e.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Automatic Noncontact Extraction and Independent Manipulation of Magnetic Particles Using Electromagnetic Needle

Seon

Cenev

Zhou

2020

IEEE/ASME Trans. Mechatron.

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Section: Discussion a Performance Analysismentioning

confidence: 99%

Section: Discussion a Performance Analysismentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Automatic Noncontact Extraction and Independent Manipulation of Magnetic Particles Using Electromagnetic Needle

Seon

Cenev

Zhou

2020

IEEE/ASME Trans. Mechatron.

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“…A robotic electromagnetic needle is a promising magnetic field-driven manipulation technique with a mobile magnetic source that can selectively manipulate microparticles [27], [12]. Seon et.…”

Section: Introductionmentioning

confidence: 99%

Non-Contact Cooperative Manipulation of Magnetic Microparticles Using Two Robotic Electromagnetic Needles

Işıtman¹,

Bettahar

Zhou

2022

IEEE Robot. Autom. Lett.

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In this paper, we report a cooperative manipulation method for non-contact robotic electromagnetic needle manipulation system. We employ two 3 degrees of freedom (DOF) robotic electromagnetic needles to achieve an over-actuated manipulator, which can move the particle to any position in the planar workspace from any direction. The redundant DOFs, combined with an optimization-based control approach, enable the manipulator to achieve accurate path following and avoid the collision of needles. Using visual servoing, the developed controller can achieve line following accuracy of 0.33±0.32 μm, square following accuracy of 0.77±0.55 μm, and circle following accuracy of 0.89±0.66 µm with a 4.5 µm diameter superparamagnetic particle. The manipulator can also manipulate a particle along complex paths such as infinity symbol and letter symbols.

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“…However, physical contact with the measurement equipment may damage the cells during the experiment. Non-contact techniques, such as optical tweezers, magnetic twisting cytometry, and dielectrophoresis (DEP) were introduced subsequently to precisely determine the mechanical properties without physical damage [10], [23]- [28]. However, harmful heat is produced from the long-term use of high-energy lasers to manipulate cells.…”

Section: Introductionmentioning

confidence: 99%

Dielectrophoretic Microfluidic Chip Integrated With Liquid Metal Electrode for Red Blood Cell Stretching Manipulation

Zhu

Cai

et al. 2019

IEEE Access

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Cellular mechanical properties are closely related to cell physiological functions and status, and their analysis and measurement help understand cell mechanism. In this study, a microfluidic platform was built to measure the mechanical properties of cells by using dielectrophoretic (DEP) force. The electrodes generally used to stretch cells are made of indium tin oxide, Au, and Pt, which have inherent disadvantages. In this paper, galinstan alloy liquid metal was first introduced as microelectrode to form non-uniform electric filed for red blood cell stretching manipulation. The liquid metal microelectrode is easy to manufacture, low in price, stable at high voltage, and reusable. An effective microfluidic chip integrated with liquid metal electrode was designed and simulated, and a series of experiments to capture and stretch red blood cells was performed. The length of the red blood cells increased from 6 µm to 8 µm under the DEP force from 0 pN to 103 pN. This work also revealed the potential use of liquid metal as microelectrode to manipulate the microparticles and cells in a microfluidic chip. INDEX TERMS Liquid metal electrode, galinstan, dielectrophoresis, microfluidic chip, cell stretching.

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Localized Manipulation of Magnetic Particles in an Ensemble

Cited by 6 publications

References 35 publications

Automatic Noncontact Extraction and Independent Manipulation of Magnetic Particles Using Electromagnetic Needle

Automatic Noncontact Extraction and Independent Manipulation of Magnetic Particles Using Electromagnetic Needle

Non-Contact Cooperative Manipulation of Magnetic Microparticles Using Two Robotic Electromagnetic Needles

Dielectrophoretic Microfluidic Chip Integrated With Liquid Metal Electrode for Red Blood Cell Stretching Manipulation

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