Localized lipoatrophy after intramuscular amikacin

Kumar, Vijay; Kumar, Manish; Grover, Chander

doi:10.4103/0378-6323.55431

Cited by 11 publications

(4 citation statements)

References 10 publications

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“…Localized after injection of the following substances has been reported in the litterature: has been reported in the literature: corticosteroids, 1,2,28 -37 insulin, 38 -43 antibiotics, 44 -46 methotrexate, 47 recombinant growth hormone, 48 soft tissue fillers, 49 glatiramer acetate, 50 -52 diphtheria–pertussis–tetanus vaccine 53 measles–mumps–rubella vaccine, 54 and influenza vaccine. 55 Most of them are associated with the involutional subtype that is characterized by a decrease in fat lobules containing small adipocytes.…”

Section: Discussionmentioning

confidence: 99%

Lipoatrophy Associated With Maxillary Bone Graft for the Purpose of Dental Implants and Correction by Fat Grafting: A Case Report

Sadeghi

Saleh

Danino

2019

Plastic Surgery Case Studies

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Lipoatrophy could be a manifestation of a metabolic disorder, pharmacological therapy, or as the result of an immune reaction in adipose tissue. Localized lipoatrophy after a dental intervention is a finding rarely described in scientific literature of head and neck pathology. A 56-year-old woman reported experiencing tissue loss on the right cheek. A maxillary bone graft for the purpose of dental implants had been performed 10 months prior to the first signs. Medical imaging showed no signs of any lytic bone lesions. A fat graft harvested from the abdomen was used to fill the deficit. For a clinician, lipoatrophy even if extremely rare should be considered among the inflammatory complications after a dento-alveolar bone graft. Especially because of its rarity, any coincidental systemic disorder should be excluded during the assessment of the condition.

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Section: Discussionmentioning

confidence: 99%

Lipoatrophy Associated With Maxillary Bone Graft for the Purpose of Dental Implants and Correction by Fat Grafting: A Case Report

Sadeghi

Saleh

Danino

2019

Plastic Surgery Case Studies

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“…[ 3 4 ] It may be iatrogenic, often involving areas of antecedent intramuscular, subcutaneous, or intra-articular injections such as insulin (non human), corticosteroids, antibiotics (amikacin, benzathine penicillin), methotrexate, bleomycin, iron, heparin, vaccines, growth factors, and glatiramer. [ 2 5 6 7 8 ] Localized lipoatrophy without any triggering factor such as injection or injury at the involved site is labelled as idiopathic.…”

Section: Discussionmentioning

confidence: 99%

Idiopathic localized involutional lipoatrophy: A retrospective study of 12 cases

Sharma¹,

Gupta²,

Negi³

2019

Indian Dermatol Online J

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“…It is also seen to be associated with nephritis, hypocomplementemia, recurrent pyogenic infections, idiopathic thrombocytopenic purpura (ITP) and thyroiditis [3]. Antiretroviral medications and acquired immunodeficiency syndrome (AIDS) and drugs like insulin, penicillin, growth hormone, steroids, glatiramer acetate, vasopressin, methotrexate, copolymer 1, iron dextran, amikacin, DPT vaccine and acupuncture have been variously reported to have caused LL [2,[4][5][6][7]. However, the exact pathogenesis of LL is not known.…”

Section: Discussionmentioning

confidence: 99%