Localized Lichen sclerosus et atrophicus of the Finger without Nail Dystrophy

Cabrera, Aloys; Rodríguez, Miguel Sáez; García‐Bustínduy, M.; Martín-Neda, Francisco Guimerá; Alom, S Dorta; García, Mercedes; González, Eva Fagundo; García, F. Rodríguez; González, R. Sánchez; Montelongo, Rafael García

doi:10.1159/000065846

Cited by 3 publications

(2 citation statements)

References 5 publications

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“…Nous en avons trouvé cinq dans la littérature : deux touchant les faces palmoplantaires [10,11], sous forme de papules kératosiques déprimées des paumes, et de papules blanches lisses ou d'érythème desquamatif sur les plantes et trois atteignant les faces dorsales [12,13,9] sous forme de papules pâles scléreuses, ou de macules érythémateuses des replis sus-unguéaux des doigts, avec parfois une onychopathie [9,12] à type d'onychodystrophie ou d'ongles striés. Les lésions décrites paraîssent similaires à celles de la malade présentée, mais aucun de ces cinq cas ne touchait les pieds et les mains sur leurs deux faces, comme dans notre observation.…”

Section: Discussionunclassified

Lichen scléreux acral

Steff

Croué

et al. 2008

Annales de Dermatologie et de Vénéréologie

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Section: Discussionunclassified

Lichen scléreux acral

Steff

Croué

et al. 2008

Annales de Dermatologie et de Vénéréologie

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“…Extragenital presentations of LS are rare [2, 3, 4]. Whereas circumcision presents a surgical treatment with benefit for male LS and the phimosis that may accompany it, vulvar LS still presents a therapeutic challenge [5, 6].…”

Section: Introductionmentioning

confidence: 99%

The Outcome after Cryosurgery and Intralesional Steroid Injection in Vulvar Lichen sclerosus Corresponds to Preoperative Histopathological Findings

Stücker¹,

Grape²,

Bechara³

et al. 2005

Dermatology

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Background: Vulvar lichen sclerosus (LS) still presents a therapeutic challenge. Questions: The aim of the present study was to investigate whether there is a correlation between preoperative histopathological findings in female LS and long-term results after cryosurgery and intralesional steroid injections. Material and Methods: 22 females with LS, mean age 65.3 ± 10.5 years, were treated with cryosurgery (–186°C) using the contact method with 1 freeze-thaw cycle per lesion and intralesional triamcinolone acetonide injection. The time between surgery and follow-up examination was 27.8 ± 14.6 months. We compared the clinical outcome and the thickness of the epidermis, the zone of sclerosis and the inflammatory infiltrate in biopsy specimens taken before treatment. Results: In 14 of 22 patients, a relapse after cryosurgery occurred (median after 7.5 months). Patients would ‘moderately’ recommend cryosurgery for LS (2.2 ± 0.9; minimum: 0, optimum: 4). Pruritus was significantly reduced (visual analog scale: preoperative 7.1 ± 2.6 vs. postoperative 2.0 ± 2.4; p = 0.001) even in patients with relapse (preoperative 7.6 ± 2.4 vs. postoperative 3.1 ± 2.28; p = 0.001). Women with relapse showed a significantly higher composed thickness of epidermis, sclerosis and inflammatory infiltrate (430 ± 139.0 µm) than those without relapse (314 ± 41.2 µm; p = 0.046). Conclusion: In our patients, cryosurgery and intralesional steroid injections were efficient in the treatment of LS. Patients showing relapse had a thicker epidermis and a stronger inflammatory infiltrate. Therefore a treatment of LS should be performed at an early stage of the disease.

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The Genital, Perianal and Umbilical Regions

Bunker¹,

Neill²

2004

Rook's Textbook of Dermatology

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Localized Lichen sclerosus et atrophicus of the Finger without Nail Dystrophy

Cited by 3 publications

References 5 publications

Lichen scléreux acral

Lichen scléreux acral

The Outcome after Cryosurgery and Intralesional Steroid Injection in Vulvar Lichen sclerosus Corresponds to Preoperative Histopathological Findings

The Genital, Perianal and Umbilical Regions

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