Localized juvenile spongiotic gingival hyperplasia

Chang, Julia Yu Fong; Kessler, Harvey P.; Wright, John M.

doi:10.1016/j.tripleo.2008.04.024

Cited by 56 publications

(115 citation statements)

References 14 publications

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“…The age of one case was not reported 2 . Furthermore, Chang et al 2 reported a female‐to‐male ratio of 2.3:1 and a racial distribution within their 52 cases of 82% white, 14% Hispanic, and 4% Asian, with three cases of unknown race. Thus, it would appear that a patient exhibiting this gingival lesion would most likely be a white female <20 years old (97% of reported cases).…”

Section: Introductionmentioning

confidence: 95%

“…A second paper, reporting 52 cases, was published in 2008 by Chang et al 2 Based on the observation of a variable epithelial hyperplasia, the authors proposed the lesion be designated as a localized juvenile spongiotic gingival hyperplasia (LJSGH). As applied to the hyperplastic epithelium, the term spongiotic implies the presentation of a sponge‐like morphology, i.e., prominent intercellular edema or spongiosis.…”

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

“…Between the two studies, 1,2 a total of 76 cases are reported, comprised of 48 females and 28 males with the following age distribution: 29 cases (38.6%) aged 5 to 10 years; 41 cases (54.6%) aged 11 to 15 years; three cases (4%) aged 16 to 20 years; and two cases (2.6%) aged ≥21 years. The age of one case was not reported 2 . Furthermore, Chang et al 2 reported a female‐to‐male ratio of 2.3:1 and a racial distribution within their 52 cases of 82% white, 14% Hispanic, and 4% Asian, with three cases of unknown race.…”

Section: Introductionmentioning

confidence: 99%

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Conservative Treatment of Localized Juvenile Spongiotic Gingival Hyperplasia

MacNeill

Rokos

Umaki

et al. 2011

Clin Adv Periodontics

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Introduction: Localized juvenile spongiotic gingival hyperplasia (LJSGH) is a recently described uncommon and distinctive form of inflammatory hyperplasia. Treatment of this condition has varied from surgical excision to no treatment followed by spontaneous remission. This case report demonstrates successful management of the lesion using a conservative treatment approach. Case Presentation: A 14‐year‐old male with negative medical and dental histories presented with LJSGH. The vivid red lesions involved the papillary and marginal gingiva of all maxillary anterior teeth. Initially, the lesion developed as a single red patch‐like area involving the maxillary left cuspid. Subsequently, the lesion displayed a linear pattern of spread to involve successively more teeth in the anterior sextant. Biopsy revealed hyperplastic elongated epithelial rete pegs, atrophy of the overlying stratified squamous epithelium with mild spongiosis, neutrophilic exocytosis, and a highly vascular connective tissue with a dominant infiltrate of chronic inflammatory cells. The lesion responded to treatment consisting of a mild surface cauterization followed by topical application of a 0.05% clobetasol ointment four times per day for a period of 4 weeks. Conclusion: This case report demonstrates that LJSGH can be successfully managed by conservative therapy, thereby avoiding potential gingival margin defects that may result from a surgical ablation of the lesion.

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Section: Introductionmentioning

confidence: 95%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Conservative Treatment of Localized Juvenile Spongiotic Gingival Hyperplasia

MacNeill

Rokos

Umaki

et al. 2011

Clin Adv Periodontics

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“…Recently, localized juvenile spongiotic gingival hyperplasia has been added to this category 4 , 20 . These lesions develop in response to local irritants such as masticatory force, defective restorations, dental plaque, calculus, trauma, and iatrogenic factor.…”

Section: Introductionmentioning

confidence: 99%

Osteopontin expression in reactive lesions of gingiva

2015

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Reactive proliferations of the gingiva comprise lesions such as pyogenic granuloma (PG), inflammatory fibroepithelial hyperplasia (IFH), peripheral ossifying fibroma (POF), and peripheral giant cell lesion. Osteopontin (OPN) has a dual role, it promotes mineralization when it is bound to solid substrate, and on the other hand, it inhibits mineralization when it is seen in association with solution.Objectives The study aimed to evaluate the expression of osteopontin in normal gingival tissue and different types of focal reactive proliferations of gingival tissue, and its role in the development of calcification within it.Material and Methods The presence and distribution of osteopontin was assessed using immunohistochemistry in five cases of normal gingival tissue and 30 cases of focal reactive proliferations of gingiva.Results There was no expression of osteopontin in normal subjects. Few cases of pyogenic granuloma, inflammatory fibroepithelial hyperplasia, and all the cases of peripheral ossifying fibroma showed positivity for osteopontin in the inflammatory cells, stromal cells, extracellular matrix, and in the calcifications.Conclusion The expression of osteopontin in all the cases of peripheral ossifying fibroma speculates that the majority of the cases of peripheral ossifying fibroma originate from the periodontal ligament cells. The treatment modalities for peripheral ossifying fibroma should differ from other focal reactive proliferations of gingiva.

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Novel treatment approach of localized juvenile spongiotic gingival hyperplasia with use of Nd:YAG laser

Goldberg

Fatahzadeh

Bortnik

et al. 2023

Clin Adv Periodontics

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IntroductionThis article describes the management of two patients who presented with localized juvenile spongiotic gingival hyperplasia. This disease entity is poorly understood, and literature regarding successful treatment is scant. However, there are common themes to management including proper diagnosis and treatment via removal of the affected tissue. The biopsy demonstrates intercellular edema and neutrophil infiltrate with epithelial and connective tissue disease components, so surgical deepithelialization may not be adequate to definitively treat the disease.Methods and ResultsThis article presents two cases of the disease and suggests the use of the Nd:YAG laser as an alternative management modality.ConclusionTo our knowledge, we present the first cases of localized juvenile spongiotic gingival hyperplasia treated with the Nd:YAG laser.Key pointsWhy are these cases new information? To our knowledge, this case series illustrates the first use of an Nd:YAG laser to treat the rare pathology localized juvenile spongiotic gingival hyperplasia. What are the keys to successful management of these cases? To properly manage this rare presentation, proper diagnosis is paramount. Following diagnosis with microscopic evaluation, deepithelialization and treatment of underlying connective tissue infiltrate via the Nd:YAG laser offers an elegant option to treat the pathology and maintain esthetic outcomes. What are the primary limitations to success in these cases? The primary limitations of these cases include the small sample size, which is attributable to the rarity of the disease.

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Localized juvenile spongiotic gingival hyperplasia

Cited by 56 publications

References 14 publications

Conservative Treatment of Localized Juvenile Spongiotic Gingival Hyperplasia

Conservative Treatment of Localized Juvenile Spongiotic Gingival Hyperplasia

Osteopontin expression in reactive lesions of gingiva

Novel treatment approach of localized juvenile spongiotic gingival hyperplasia with use of Nd:YAG laser

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