Localized giant pseudopolyposis of the colon in ulcerative colitis

Kovalcik, Paul J.; Szydlowski, Thaddeus

doi:10.1007/bf02587098

Cited by 14 publications

(14 citation statements)

References 6 publications

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“…PPs have been described in association with ulcerative colitis (UC) as far back as 1926, although the modern identifier terminology was not used at that time[2]. Their name originated as an effort to separate them from the true neoplastic polyps, namely adenomas[3]. …”

Section: Introductionmentioning

confidence: 99%

Pseudopolyps in inflammatory bowel diseases: Have we learned enough?

Politis

Κατσάνος

Tsianos

et al. 2017

WJG

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Pseudopolyps are a well described entity in the literature and even though the exact pathogenesis of their formation is not completely understood, they are considered non-neoplastic lesions originating from the mucosa after repeated periods of inflammation and ulceration associated with excessive healing processes. Their occurrence is less common in Crohn's disease than in ulcerative colitis, and their overall prevalence ranges from 4% to 74%; moreover, they are found more often in colon but have been detected in other parts of the gastrointestinal tract as well. When their size exceeds the arbitrary point of 1.5 cm, they are classified as giant pseudopolyps. Clinical evaluation should differentiate the pseudopolyps from other polypoid lesions, such as the dysplasia-associated mass or lesion, but this situation represents an ongoing clinical challenge. Pseudopolyps can provoke complications such as bleeding or obstruction, and their management includes medical therapy, endoscopy and surgery; however, no consensus exists about the optimal treatment approach. Patients with pseudopolyps are considered at intermediate risk for colorectal cancer and regular endoscopic monitoring is recommended. Through a review of the literature, we provide here a proposed classification of the characteristics of pseudopolyps.

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Section: Introductionmentioning

confidence: 99%

Pseudopolyps in inflammatory bowel diseases: Have we learned enough?

Politis

Κατσάνος

Tsianos

et al. 2017

WJG

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“…It can also produce obstruction and intussusceptions in addition to bleeding 24,25. Ulceration of polyps and subsequent hemorrhage appears to be the result of trauma caused by fecal flow and peristalsis 1,26,27. Rare cases presenting as toxic megacolon have been reported 28…”

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confidence: 99%

“…To date, FP themselves are not considered precancerous and not an indication to operate 3,15,17,19,21,26,27. Many unnecessary colectomies have been performed for inflammatory polyps 22.…”

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confidence: 99%

What is the Clinical Relevance of Filiform Polyposis?

Lim¹,

Choi²,

Yang³

2012

Gut Liver

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“…In rare cases, the polyps are present in large numbers and of a large size, and such a condition has been referred to as giant inflammatory polyposis. [4][5][6] Kelly et al 2 reported that giant inflammatory polyposis was found in 4 (4.6%) of 86 colectomized patients with IBD. A review of 53 patients with giant inflammatory polyposis revealed that two-thirds of the patients had Crohn's disease and one-third had UC.…”

Section: Discussionmentioning

confidence: 98%

Colonic obstruction due to giant inflammatory polyposis in a patient with ulcerative colitis

et al. 2005

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A 32-year-old Japanese woman with a 14-month history of ulcerative colitis (UC), pancolitis type, was referred to our institution, because of abdominal distention. Plain abdominal X-ray and computed tomography (CT) showed marked dilatation of the right side of the colon. The patient was treated by immediate total colectomy, with the diagnosis of toxic megacolon. Macroscopically, there was a constricting lesion with giant polyposis in the middle part of the transverse colon. Histologically, there was transmural inflammation with a thickened proper muscular layer overlaid by inflammatory polyposis. This case suggests that giant polyposis in UC patients may result in severe stenosis and that such a condition should not be misinterpreted as toxic megacolon or as colitic cancer.

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Localized giant pseudopolyposis of the colon in ulcerative colitis

Cited by 14 publications

References 6 publications

Pseudopolyps in inflammatory bowel diseases: Have we learned enough?

Pseudopolyps in inflammatory bowel diseases: Have we learned enough?

What is the Clinical Relevance of Filiform Polyposis?

Colonic obstruction due to giant inflammatory polyposis in a patient with ulcerative colitis

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