Localized gastric mucosal hypertrophy simulating tumor

Sussman, Howard M.; Weingarten, Berthold; Mossberg, Sanford M.

doi:10.1007/bf02236071

Cited by 17 publications

(8 citation statements)

References 17 publications

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“…The solid portion was relatively obvious (mucosal polypoid hyperplasia) and was often accompanied by fine pointlike cystic changes internally [4][5][6][7][8][9][10]12]. However, this cohort only had one case similar to the reports in the literature, whereas the remaining cases were primarily dominated by the cystic component, with thick mucosal hyperplasia on the surface.…”

Section: Discussionmentioning

confidence: 85%

“…As shown in previous studies [1,2], GCP mostly occurs after partial gastrectomy, and has a significant correlation with early gastric cancer [3]. It has been reported that GCP also occurs in patients with no history of gastric surgery, but this is very rare [4]. In order to distinguish these cases from secondary GCP due to partial gastrectomy, we referred to them as primary GCP.…”

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confidence: 95%

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Imaging, endoscopy, and pathologic findings of primary gastritis cystica polyposa: description of a rare entity in a small case series

Gong

et al. 2016

Abdom Radiol

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Primary GCP has relatively particular endoscopy features, which can be accurately diagnosed by gastroscopy when the lesion is small. But endoscopy has its limitations in the diagnosis and differentiation for some large lesions. In contrast to gastroscopy and gastroscopic ultrasound, CT or MRI provides more information about both the gastric wall and the extragastric extent of the disease, which is more helpful for differential diagnosis and surgical planning of GCP before operation.

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Section: Discussionmentioning

confidence: 85%

mentioning

confidence: 95%

Imaging, endoscopy, and pathologic findings of primary gastritis cystica polyposa: description of a rare entity in a small case series

Gong

et al. 2016

Abdom Radiol

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“…[24][25][26] In the English literature, these cysts are reported to occur predominantly in the gastric body or fundus at sites of prior surgical anastomoses in Caucasian patients. 25 Although prior injury, ischemia, and chronic inflammation may be central to the pathogenesis of these cysts, 25,26 the slow disruption of the MM over years may ultimately allow for the migration of benign cardiac glands in the lamina propria through the frayed, fragmented MM into the submucosal space, with subsequent cystic dilation. Our study results support this speculation, as none of our patients had a history of gastric cardiac surgery or other type of trauma.…”

Section: Discussionmentioning

confidence: 99%

“…24 Although it is difficult to do so, the accurate recognition of these cysts is very important to avoid a misdiagnosis of gastric cardiac carcinoma with a consequence of unnecessary radical gastrectomy. 26 The significantly increased prevalence of these submucosal cysts in EGCC of Chinese patients requires further scrutiny.…”

Section: Discussionmentioning

confidence: 99%

Marked thickening of muscularis mucosae and submucosa in the gastric cardia: A histopathological study of 110 surgical resection cases

Huang

Shi

Liu

et al. 2020

J of Digest Diseases

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Objective: To investigate histopathologic changes of muscularis mucosae (MM) and submucosa in the gastric cardia. Methods:We performed a histopathology study of 50 distal esophagectomies with proximal gastrectomies for esophageal squamous cell carcinoma as the study (noncancerous cardiac) group and 60 gastrectomies for early gastric cardiac carcinoma as the cancer group. The gastroesophageal junction was defined as the distal end of squamous epithelium, multilayered epithelium, or deep esophageal glands or ducts.Gastric cardia (n = 110) was defined as the presence of cardiac and cardio-oxyntic mucosae distal to the gastroesophageal junction.Results: The average thickness of MM and submucosa in the cardia was 1.04 and 1.41 mm, respectively, which was significantly thicker than that in distal stomach (n = 34) (0.22 and 0.99 mm) or distal esophagus (n = 92) (0.60 and 1.15 mm). In the cardia, thickened MM displayed frayed muscle fibers (93.3%) with a significantly higher prevalence of entrapped glands, cysts, and lymphoid follicles than in the distal stomach or distal esophagus. In the submucosa fatty changes, cysts, and abnormal arteries were significantly more common in the cardia than in the distal stomach or distal esophagus. Compared with the study group, the cardia in the cancer group showed significantly thicker MM (average 1.31 vs 0.72 mm) and submucosa (average 1.61 vs 1.16 mm), more frequent frayed MM (93.3% vs 60.0%), prolapse-like changes (50.0% vs 2.0%), and cysts (26.7% vs 4.0%).Conclusion: MM and submucosa of the cardia were significantly thickened, especially in early gastric cardiac carcinomas.

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“…Very few cases of GCP were observed in unoperated stomachs. 7–10 Although there have been several reports on the application of endoscopic mucosal resection (EMR) for GCP, we know of no reported case of EMR application on GCP in an unoperated stomach after close examination by endoscopic ultrasonography (EUS) and other diagnostic modalities.…”

Section: Introductionmentioning

confidence: 99%

A case of gastritis cystica polyposa showing a characteristic endoscopic ultrasonogram

Shudo¹,

Horita²,

Takahashi³

et al. 2000

Digestive Endoscopy

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Littler reported on the torose polypoid lesion observed at the site of gastroenterostomy long after gastrectomy and called it gastritis cystica polyposa (GCP). Since then, much attention has been paid to hypertrophic lesions at the sites of gastroenterostomy, and many reports on GCP have been published. This lesion often develops in patients who had gastroenteroanastomosis. It was observed by the authors that a submucosal tumor developed at the cardiac part of the stomach in a patient who had no history of gastrectomy. Very few cases of GCP were observed in unoperated stomachs. The tumor was excised by endoscopic mucosal resection and diagnosed histopathologically as GCP. Endoscopic ultrasonography before the operation revealed the presence of a spongy body filled with anechoic areas of various sizes under the mucosa of the tumor. This finding is characteristic of this disorder and is detailed here with a discussion on related papers.

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Localized gastric mucosal hypertrophy simulating tumor

Cited by 17 publications

References 17 publications

Imaging, endoscopy, and pathologic findings of primary gastritis cystica polyposa: description of a rare entity in a small case series

Imaging, endoscopy, and pathologic findings of primary gastritis cystica polyposa: description of a rare entity in a small case series

Marked thickening of muscularis mucosae and submucosa in the gastric cardia: A histopathological study of 110 surgical resection cases

A case of gastritis cystica polyposa showing a characteristic endoscopic ultrasonogram

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