Localized Basaloid Follicular Hamartoma

Kato, Naoko; Ueno, Hiroo; Nakamura, Junnosuke

doi:10.1111/j.1346-8138.1992.tb03739.x

Cited by 15 publications

(15 citation statements)

References 10 publications

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“…The acquired variants of BFH include localized and solitary forms. Localized BFH may present as a soft, hairless, irregularly elevated plaque in the retroauricular area 15 . Or it may present as a localized plaque of scalp alopecia 1 .…”

Section: Discussionmentioning

confidence: 99%

Basaloid follicular hamartoma

et al. 2005

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Basaloid follicular hamartoma (BFH) is a unique benign follicular hamartoma characterized by variable clinical presentations, identical histologic features and possible associations with numerous disorders. Basaloid follicular hamartoma may be hereditary or acquired. Hereditary cases may be either generalized or unilateral nevoid. Although the generalized forms are usually associated with systemic manifestations, such as myasthenia gravis,(2) it may occasionally present without internal disorders. On the other hand, the acquired forms of BFH may present in the form of localized or solitary forms. Herein we present four cases of BFH, one of them (first case) represents a unique form of the generalized variant of BFH, showing no associated internal disorders.

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Section: Discussionmentioning

confidence: 99%

Basaloid follicular hamartoma

et al. 2005

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“…reported non‐familial linear epidermal naevus‐like plaques, which histopathologically were basaloid follicular hamartomas. In addition, several cases of basaloid follicular hamartomas or closely related hair follicle hamartomas presenting with alopecia and myasthenia gravis have been reported 6–9 and rare reports of large plaques on the scalp with associated alopecia have been noted 3,10 . Three cases of autosomal dominantly transmitted multiple basaloid follicular hamartomas have been documented.…”

Section: Discussionmentioning

confidence: 99%

Multiple basaloid follicular hamartomas associated with acrochordons, seborrhoeic keratoses and chondrosarcoma

2002

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Basaloid follicular hamartoma is an uncommon neoplasm with distinctive histopathological findings. It presents as four distinctive clinical forms: a solitary papule, a localized plaque of alopecia, a localized linear and unilateral type, and generalized papules with associated alopecia and myasthenia gravis. Histologically, basaloid follicular hamartomas are characterized by thin branching strands and thick cords of basaloid or squamoid cells extending from a follicle into a loose, fibrillar, fibrocytic or mucinous connective tissue stroma. We report a case of long-standing, generalized basaloid follicular hamartomas associated with acrochordons, seborrhoeic keratoses, and a history of chondrosarcoma. In general, solitary tumours are sporadic; multiple tumours are inherited and frequently associated with a syndrome. Further surveillance is warranted to determine if the association of multiple basaloid follicular hamartomas and chondrosarcoma constitutes an inherited syndrome.

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“…The term ‘basaloid follicular hamartoma’ was coined by Mehregan and Baker 2 in 1985. BFH is alleged to assume five different clinical forms: (i) an acquired generalized type with myasthenia gravis and diffuse alopecia; 1 (ii) a generalized type, without any associated diseases; 6 (iii) a congenital generalized type, associated with cystic fibrosis and diffuse alopecia; 7 (iv) a localized linear and unilateral type; 2,3 and (v) a solitary plaque or nodular type 2 (one report 7 of which may represent trichoblastoma arising in nevus sebaceous and another 8 which may be infundibulocystic basal cell carcinoma). Multiple BFH may be cutaneous marker of systemic diseases or more complex familial syndrome.…”

Section: Reportmentioning

confidence: 99%