Localized and Systemic Hypersensitivity Reactions to Human Seminal Fluid

Investigation of Seminal Plasma Hypersensitivity Reactions

“…This questionnaire has been validated as reliable in detecting women with probable local and/or systemic seminal plasma hypersensitivity reactions. 3 This questionnaire was completed by the sexual partners of 52 GW veterans. Table II summarizes and compares questionnaire #2 responses obtained from the sexual partners of GW veterans (N=52) to a group of civilian females seeking medical attention for symptoms suggestive of localized and/or systemic seminal plasma protein hypersensitivity (N=34) and a population of women previously reported in the literature diagnosed with seminal plasma protein hypersensitivity.…”

Investigation of Seminal Plasma Hypersensitivity Reactions (AIBS GWI 0046)

“…The seminal plasma was then aliquoted and frozen at -75°C. 2 Previous comparison studies evaluating SDS-PAGE protein patterns of fresh whole seminal plasma to pooled ejaculates collected and stored over several days revealed no differences in their protein patterns.…”

Anaphylaxis and Human Seminal Plasma Allergy: A Review

“…Women aged 20 -30 years are most affected, displaying symptoms immediately or up to 1 h after exposure [16] .…”

“…Local reactions include itching, erythema and oedema in the vulvar region, or other areas, which have been in contact with semen. Systemic reactions include dyspnoea, dysphagia, rhinoconjunctivitis, generalised urticaria, angioedema gastrointestinal symptoms, and exacerbation of atopic eczema [16,18] …”