Localized and persistent erythema nodosum leprosum - a rare variant?

Prabhu, Smitha; Rao, Raghavendra; Sripathi, H; Rao, Laxmi; Singh, Ridhi

doi:10.5070/d32xv335d1

Cited by 4 publications

(4 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…described a presentation of ENL as localised but the erythematous, painful papules and nodules on the posterolateral aspects of both thighs were associated new nodules on the face and upper extremities. The presentation described appeared to be in keeping with the widespread cutaneous lesions commonly seen in ENL 15 …”

Section: Case Reportsupporting

confidence: 67%

“…The presentation described appeared to be in keeping with the widespread cutaneous lesions commonly seen in ENL. 15 Localised ENL may be difficult to diagnose due to the rarity and limited extent of disease in contrast to the typical generalised nature of ENL. The localised form we report here appears to follow a chronic course as is commonly seen in ENL and despite being localised required treatment with thalidomide.…”

Section: Case Reportmentioning

confidence: 99%

“…The presentation described appeared to be in keeping with the widespread cutaneous lesions commonly seen in ENL. 15 …”

Section: Case Reportmentioning

confidence: 99%

See 2 more Smart Citations

Localised erythema nodosum leprosum—A rare entity managed with thalidomide

Patel,

De Barros,

Walker

2024

Skin Health and Disease

View full text Add to dashboard Cite

Leprosy is caused by Mycobacterium leprae. The condition primarily affects the skin and peripheral nerves. There are two types of leprosy reactions, Type 1 and Type 2 or erythema nodosum leprosum (ENL). ENL is a severe multi‐system, immune‐mediated complication of lepromatous leprosy. It is characterised by widespread painful cutaneous nodules, fever and peripheral oedema. This report discusses the unusual case of a 29‐year‐old woman who developed a localised form of ENL which required thalidomide to induce remission.

show abstract

Section: Case Reportsupporting

confidence: 67%

Section: Case Reportmentioning

confidence: 99%

See 1 more Smart Citation

Localised erythema nodosum leprosum—A rare entity managed with thalidomide

Patel,

De Barros,

Walker

2024

Skin Health and Disease

View full text Add to dashboard Cite

show abstract

“…3 Chronic cases lasting longer than 2 years have been reported in patients infected with Mycobacterium leprae strains resistant to treatment. 3,[6][7][8] Histologically ENL is composed of vacuolated or "foamy" macrophages, lymphocytes, and plasma cells, with a conspicuous neutrophilic infiltrate in the subcutis and panniculitis with or without vasculitis. When vasculitis is present, it is classically neutrophilic, but the timing of the biopsy can greatly affect whether neutrophils are present, with a precipitous decrease in neutrophils seen 1 week after the appearance of ENL symptoms.…”

Section: Introductionmentioning

confidence: 99%

Type 2 Leprosy Reaction Mimicking Leukocytoclastic Vasculitis in a Postpartum Patient

Schaffenburg,

Royer,

Scorza

2023

The American Journal of Dermatopathology

View full text Add to dashboard Cite

Leprosy is a disease caused by Mycobacterium leprae that, depending on a patient's baseline susceptibility and immune system function, can present in a wide variety of ways. The host's immune system response to the infection can be cell-mediated or humoral and can be further altered by changes in immune function or treatment. Depending on the time at which a skin biopsy is taken from affected areas, different inflammatory cell types are present, and the histopathology can mimic that of other infectious, autoimmune, or malignant entities, especially when the clinical information provided is vague. We present a case of a 24-year-old Micronesian woman who initially presented immediately postpartum with clinical and histopathological findings suggestive of urticarial vasculitis, but a subsequent biopsy resulted in a diagnosis of erythema nodosum leprosum reaction and borderline multibacillary leprosy. This case illustrates an unusual clinical and histological presentation of M. leprae and highlights the importance of clinical history.

show abstract

Lipoid proteinosis: A case report with recurrent parotitis and intracranial calcifications

Al-Ekrish

Al‐Sadhan

2012

King Saud University Journal of Dental Sciences

View full text Add to dashboard Cite

Lipoid proteinosis is an autosomal recessive disease of abnormal deposition of glycoprotein in various tissues. Symptoms may include a hoarse voice, lesions and scarring on the skin, easily damaged skin with poor wound healing, dry, wrinkly skin, and beading of the papules around the eyelids. Calcifications of brain tissue can lead to epilepsy and neuropsychiatric abnormalities. In this paper we will review the current literature on the disease and report a case of a 15 year old Saudi female with lipoid proteinosis that presented initially with recurrent parotitis.

show abstract

Localized and persistent erythema nodosum leprosum - a rare variant?

Cited by 4 publications

References 0 publications

Localised erythema nodosum leprosum—A rare entity managed with thalidomide

Localised erythema nodosum leprosum—A rare entity managed with thalidomide

Type 2 Leprosy Reaction Mimicking Leukocytoclastic Vasculitis in a Postpartum Patient

Lipoid proteinosis: A case report with recurrent parotitis and intracranial calcifications

Contact Info

Product

Resources

About