Localized Amyloidosis of the Orbit and Upper Respiratory Tract

Kaiser-Kupfer, M. I.; Kuwabara, Toichiro

doi:10.1016/0002-9394(77)90391-9

Cited by 10 publications

(1 citation statement)

References 15 publications

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“…Together with this present review, a total of 52 cases of oral localized amyloidosis were found in the literature. The majority of the cases was observed in female patients (53.84%) 10,11,13,14,17,18,[20][21][22][24][25][26][28][29][30]32,[34][35][36] , with an average age of 55,4 years (range 9 to 90 years) and the tongue as the most common localization (49.12%) 4,10,16,[19][20][21][22][26][27][28]30,[33][34][35][36]38 . All data of this review are consistent with the present case reported.…”

Section: Discussionmentioning

confidence: 99%

Oral localized amyloidosis

Ferreira¹,

Campolina²,

Oliveira³

et al. 2022

J Oral Diag

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Introduction: Amyloidosis is a condition related to aggregates of proteins in several organs of the body and can be systemic or localized. Amyloidosis localized in the oral cavity is extremely rare, being the tongue the more prevalent region. Objective: The aim of this present study is to describe a case of localized amyloidosis on the tongue and surgically removed. Methods: Also, a review of English-language literature of oral loca-lized amyloidosis from 1946 to 2021 was performed. Results: A total of 52 cases of oral localized amyloidosis were found in the literature. The majority of the cases was observed in female patients (53,84%), with an average age of 55,4 years (range 9 to 90 years) and the tongue being the most common localization (49,12%). Conclusions: Amyloidosis is a rare condition with atypical sign and symptoms. The systemic involvement should be evaluated due to worse prognosis of this condition and the possibility of organs failures. There is no standard treatment for local amyloidosis, but surgical excision is indicated to reduce the functional prejudice and pain, in symptomatic cases.

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Section: Discussionmentioning

confidence: 99%

Oral localized amyloidosis

Ferreira¹,

Campolina²,

Oliveira³

et al. 2022

J Oral Diag

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Experimental models

1981

Arthritis & Rheumatism

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Light and electron microscopic studies of localized laryngeal amyloidosis

Nagata

Yoshihara

Nomoto

et al. 1987

Arch Otorhinolaryngol

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We performed light and electron microscopic studies in a case of localized supraglottic laryngeal amyloidosis involving a 55-year-old woman. Tissue specimens were stained with hematoxylin and eosin, and alkaline Congo red with or without permanganate (KMnO4) treatment, and were also examined with peroxidase-antiperoxidase immunohistochemistry. Biopsy specimens from the epiglottis showed diffuse replacement of the subepithelial region by amyloid, which showed a typical green birefringence under polarized light. Tissue affinity for Congo red was persistent after the KMnO4 treatment. However, the tissue sections showed a positive reaction only to the anti-P component antibody. Electron microscopic studies revealed some disorders of the plasma cells, suggesting that these cells play an important role in focal production of amyloid fibrils.

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Localized Amyloidosis of the Orbit and Upper Respiratory Tract

Cited by 10 publications

References 15 publications

Oral localized amyloidosis

Oral localized amyloidosis

Experimental models

Light and electron microscopic studies of localized laryngeal amyloidosis

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