1978
DOI: 10.3758/bf03326725
|View full text |Cite
|
Sign up to set email alerts
|

Localization of a “passive avoidance memory system”in the white rat

Abstract: Adult rats, previously trained to refrain from entering a small dark compartment from a large illuminated compartment, sustained lesions to 1 of 53 different brain sites and were subsequently tested for retention. Retention losses were associated with lesions to the neocortex, most elements of the limbic forebrain and basal ganglia, medial portions of the thalamus and hypothalamus, colliculi, median raphe, and cerebellum. Most of these structures were also found to be critical for retention of an active avoida… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
2
1

Citation Types

0
10
0

Year Published

1984
1984
2003
2003

Publication Types

Select...
6

Relationship

2
4

Authors

Journals

citations
Cited by 42 publications
(10 citation statements)
references
References 48 publications
0
10
0
Order By: Relevance
“…This would follow from the fact that the latter would also disrupt hippocampal function to the extent that the hippocampus would be deprived of certain kinds of sensory input necessary to transact its comparator role. This account would seem to explain the similar disturbances observed in neocortically and hippocampally damaged rats on such tasks as complex mazes (Foreman & Stevens, 1982;Thompson, 1979), position reversals (Thompson, 1983), and active and passive avoidance responses (Thompson, 1978b).…”
Section: Nature Of the Deficitmentioning
confidence: 82%
See 1 more Smart Citation
“…This would follow from the fact that the latter would also disrupt hippocampal function to the extent that the hippocampus would be deprived of certain kinds of sensory input necessary to transact its comparator role. This account would seem to explain the similar disturbances observed in neocortically and hippocampally damaged rats on such tasks as complex mazes (Foreman & Stevens, 1982;Thompson, 1979), position reversals (Thompson, 1983), and active and passive avoidance responses (Thompson, 1978b).…”
Section: Nature Of the Deficitmentioning
confidence: 82%
“…Rats with hippocampal or neocorticallesions have been characterized, at one time or another, as showing a disturbance in response inhibition (Douglas, 1967;Gray, 1982;Thompson, 1978b), recent ("working") memory (Lashley, 1929;Olton & Papas, 1979), behavioral exploration (Lashley, 1935;O'Keefe & Nadel, 1978), and/or attention (Lashley, 1935;Oades, 1982). Any one of these disturbances could underlie the reduction in response flexibility reported in the current experiment.…”
Section: Nature Of the Deficitmentioning
confidence: 99%
“…However, evidence supporting the existence of an inhibitory deficit in these subcortically lesioned rats comes from other sources as well. For example, rats with damage to any one of the subcortical sites studied in the current experiment have been reported to show impairments in spatial reversal learning (Thompson, 1983) and those with damage to the GP, SN, or MR have been found to show retention impairments of a passive avoidance response (Thompson, 1978b). Tasks of this sort have likewise been viewed as being sensitive to an inhibitory deficit (Warburton, 1977).…”
Section: Deficits In Response Inhibition and Attention 495mentioning
confidence: 95%
“…For example, the hippocampus of rodents has been implicated in both inhibitory (Douglas, 1967) and attentional (Oades, 1982) processes; yet young or adult rats with hippocampal lesions do not exhibit a generalized learning impairment (Douglas, 1967;Thompson, 1982a;Thompson & Yu, 1983). Other brain regions, to mention a few, which have been implicated in one or both of these processes include the frontal cortex (Stuss Thompson, 1978b), amygdala (Nagel & Kemble, 1976;Thompson, 1978b), and lateral lemniscal midbrain area (Sprague, Levitt, Robson, Liu, Stellar, & Chambers, 1963). Again, damage to these regions in young or adult rats does not result in a generalized learning impairment (Thompson, 1982a(Thompson, , 1983Thompson, Ramsay, & Yu, 1984).…”
Section: Deficits In Response Inhibition and Attention 495mentioning
confidence: 99%
“…This fear-motivated learning is an hippocampal-dependent task that is acquired in a single and brief training session (Winocur and Bindra, 1976;Thompson, 1977;Gold, 1986;Lorenzini et al, 1996;Taubenfeld et al, 1999), which makes it ideal for investigating the role of signaling pathways initiated during memory processing without the interference from retrieval of the learned behavior that might occur in multitrial tasks .…”
Section: Rapid and Transient Induction Of Bdnf Mrna In Hippocampus Dumentioning
confidence: 99%