Localización radioguiada de lesiones ocultas de mama (ROLL)

Romera, M. Cortés; García, Ricardo Pardo; Castrejón, Á. Soriano; Vicente, A. García; Díaz, Marrero; García, V.M. Poblete; Vicente, Miguel; Marina, S. Rodado; Solís, S. Ruíz; Rubio, P. Talavera

doi:10.1016/s0212-6982(05)74181-1

Cited by 21 publications

(1 citation statement)

References 7 publications

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“…In conclusion, ROLL seems to be a simple, accurate, and relatively safe technique compared with the current standard of WGL 106–109. Further research is needed to elucidate the position of ROLL for the treatment of nonpalpable breast tumors.…”

Section: Future Directionsmentioning

confidence: 87%

Obtaining Adequate Surgical Margins in Breast-Conserving Therapy for Patients with Early-Stage Breast Cancer: Current Modalities and Future Directions

et al. 2009

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Inadequate surgical margins represent a high risk for adverse clinical outcome in breast-conserving therapy (BCT) for early-stage breast cancer. The majority of studies report positive resection margins in 20% to 40% of the patients who underwent BCT. This may result in an increased local recurrence (LR) rate or additional surgery and, consequently, adverse affects on cosmesis, psychological distress, and health costs. In the literature, various risk factors are reported to be associated with positive margin status after lumpectomy, which may allow the surgeon to distinguish those patients with a higher a priori risk for re-excision. However, most risk factors are related to tumor biology and patient characteristics, which cannot be modified as such. Therefore, efforts to reduce the number of positive margins should focus on optimizing the surgical procedure itself, because the surgeon lacks real-time intraoperative information on the presence of positive resection margins during breast-conserving surgery. This review presents the status of pre- and intraoperative modalities currently used in BCT. Furthermore, innovative intraoperative approaches, such as positron emission tomography, radioguided occult lesion localization, and near-infrared fluorescence optical imaging, are addressed, which have to prove their potential value in improving surgical outcome and reducing the need for re-excision in BCT.

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Section: Future Directionsmentioning

confidence: 87%

Obtaining Adequate Surgical Margins in Breast-Conserving Therapy for Patients with Early-Stage Breast Cancer: Current Modalities and Future Directions

et al. 2009

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Radioguided occult lesion localisation in breast cancer using an intraoperative portable gamma camera: first results

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Vidal-Sicart

Zanón

et al. 2007

Eur J Nucl Med Mol Imaging

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Surgical margins in conservative surgery for breast cancer

et al. 2009

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Conservative surgery is the actual gold standard for the management of low-stages (i.e. I and II) breast cancers. The completion of clear margins is a prerequisite for a complete local treatment and a decrease of local recurrences. A tight collaboration between pathologists and surgeons is mandatory. There is no consensus for the definition of the cut of a clear margin. Different management processes have been reported through the literature, ranging from gross management to cytologic or histopathologic methods for margin evaluation. Such approaches have to be correlated to the clinical and radiological setting. They have to be performed in line with tumor characteristics, and treatment plans. The perspectives are a better evaluation of surgical margins using nuclear medicine or molecular biology tools to decrease the number of second surgical procedures.

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Localización radioguiada de lesiones ocultas de mama (ROLL)

Cited by 21 publications

References 7 publications

Obtaining Adequate Surgical Margins in Breast-Conserving Therapy for Patients with Early-Stage Breast Cancer: Current Modalities and Future Directions

Obtaining Adequate Surgical Margins in Breast-Conserving Therapy for Patients with Early-Stage Breast Cancer: Current Modalities and Future Directions

Radioguided occult lesion localisation in breast cancer using an intraoperative portable gamma camera: first results

Surgical margins in conservative surgery for breast cancer

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