Localised reaction following Patent Blue V and morphine injections

N, McLoughlin; Mathers, Helen; O'Hare, Ciara

doi:10.1111/anae.12111

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“…Opiates are known to cause histamine release that may result in cutaneous adverse drug reactions such as urticaria, erythema, pruritus, and sometimes pseudoallergic anaphylactoid reactions . In our case, the patient experienced a non‐IgE‐mediated urticarial reaction to the morphine injection which was tinted blue due to prior subareolar injection of Patent Blue V dye into her left breast.…”

Section: Discussionmentioning

confidence: 80%

Blue urticaria following Patent Blue V and morphine injections

Koumaki

Orton

2020

Clinical Case Reports

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We present a patient with a non-IgE-mediated urticaria reaction to the morphine injection which was tinted blue due to prior injection of Patent Blue V dye into her left breast. Clinicians should be aware of these types of reaction to morphine. K E Y W O R D Sdirect histamine release, morphine injection, non-IgE-mediated localized reaction, Patent Blue V F I G U R E 1 Localized blue wheals following morphine injection on the right arm 924 | KOUMAKI And ORTOn erythema, pruritus, and sometimes pseudoallergic anaphylactoid reactions. 1,2 In our case, the patient experienced a non-IgE-mediated urticarial reaction to the morphine injection which was tinted blue due to prior subareolar injection of Patent Blue V dye into her left breast.

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Section: Discussionmentioning

confidence: 80%