Localisation orbitaire de l’histiocytose langerhansienne dans sa forme multiviscérale

Abdellaoui, M.; Benatiya, A.I.; Bhallil, S.; Tahri, H.

doi:10.1016/j.arcped.2011.03.018

Cited by 3 publications

(5 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…В тяжелых случаях высыпания на коже приобретают генерализованный характер, наблюдаются петехиальные кровоизлияния (рис. 2), при этом поражение ладоней и подошв служит неблагоприятным прогностическим признаком [37,41]. Высыпания также могут быть представлены папулами, в центре которых формируется некроз (рис.…”

Section: клиническая картинаunclassified

“…Реже заболевание выражено диссеминированными эритематозно-сквамозными папулами, похожими на проявления болезни Абта -Леттерера -Сиве, но в меньшем количестве и без геморрагического компонента. После разрешения элементов сыпи могут образовываться поствоспалительные рубцы [37,41].…”

Section: клиническая картинаunclassified

“…Несахарный диабет -распространенное (до 50% случаев) и потенциально необратимое явление при болезни Хэнда -Шуллера -Кристиана. Манифестация его может произойти спустя годы после или за несколько лет до установления диагноза [37,41,47,48]. Экзофтальм наблюдается приблизительно у 10% пациентов и возникает вследствие поражения костей черепа, а именно периорбитальной области, которое может сопровождаться нарушением зрения вплоть до его полной потери (рис.…”

Section: клиническая картинаunclassified

“…Экзофтальм наблюдается приблизительно у 10% пациентов и возникает вследствие поражения костей черепа, а именно периорбитальной области, которое может сопровождаться нарушением зрения вплоть до его полной потери (рис. 4) [30,41,46]. Поражение костей наблюдается у 80% пациентов с данной формой заболевания, у трети пациентов мишенью становятся легкие.…”

Section: клиническая картинаunclassified

See 3 more Smart Citations

Langerhans cell histiocytosis as a clonal disease of mononuclear phagocyte system

Khynku¹,

Monaenkova²,

Tamrazova³

et al. 2023

Almanac of Clinical Medicine

View full text Add to dashboard Cite

Langerhans cell histiocytosis (LCH) belongs to histiocytic proliferative diseases, which are rare in clinical practice; however they pose significant challenges both for their diagnosis and choice of therapeutic strategies. Histiocytic proliferative diseases are the scope of oncology; nevertheless, at the diagnostic stage the patients are referred to pediatricians or dermatologists. That is why the interdisciplinary interaction of various specialties and common approaches to their classification, diagnosis and treatment are important for the management of patients with histiocytic proliferative disorders. Accumulation of the studies on the LCH pathophysiology has promoted the development of new diagnostic algorithms and treatment methods. After the fact of MAPK signal pathway activation had been established, the potential target for therapy was identified. Neoplastic nature of LCH has been hypothesized. If confirmed, we can expect actual diagnostic algorithms being elaborated, in particular, the potential to predict the disease depending on the tumor clone mutation type. The unique characteristics of LCH including proliferate clonality (presumable of neoplastic nature), the disease course with spontaneous regression and frequent relapses and tropism to certain tissues (target organs) make up the grounds for further in-depth studies of the disease.

show abstract

Section: клиническая картинаunclassified

See 2 more Smart Citations

Langerhans cell histiocytosis as a clonal disease of mononuclear phagocyte system

Khynku¹,

Monaenkova²,

Tamrazova³

et al. 2023

Almanac of Clinical Medicine

View full text Add to dashboard Cite

show abstract

“…Langerhans Cell Histiocytosis accounts for less than 1% of orbital tumors ( 14 , 15 ). In our patient one of the striking physical examination finding and one of the first finding of the disease was left sided exophtalmos which was a consequence of a mass lesion approximately 4 cm in maximum diameter, invading the globe with intracranial projection and infiltrating the bone tissue.…”

Section: Case Reportmentioning

confidence: 99%

Insufficiency of Bone Scintigraphy in Vertebral Lesions of Langerhans Cell Histiocytosis Compared to F-18 Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography and Diagnostic Computed Tomography

Koç

Şimşek²,

Akarsu³

et al. 2015

Mirt

View full text Add to dashboard Cite

Langerhans cell histiocytosis (LCH) is a benign disorder related to the histiocytes which can infiltrate bone tissue. The most effective method for demonstrating severity of this disease is PET/CT and bone scintigraphy might show bone lesions. We present a seventeen year old male patient with disseminated LCH presented with exophtalmos and having multiple vertebral lesions which were identified by F-18 FDG PET/CT scan and diagnostic CT but not in the bone scintigraphy.

show abstract

Histocitiosis de células de Langerhans en su presentación focalizada en órbita

Mendoza¹,

Interlomas

Flores

et al. 2019

Rev Fac Med

View full text Add to dashboard Cite

Localisation orbitaire de l’histiocytose langerhansienne dans sa forme multiviscérale

Cited by 3 publications

References 13 publications

Langerhans cell histiocytosis as a clonal disease of mononuclear phagocyte system

Langerhans cell histiocytosis as a clonal disease of mononuclear phagocyte system

Insufficiency of Bone Scintigraphy in Vertebral Lesions of Langerhans Cell Histiocytosis Compared to F-18 Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography and Diagnostic Computed Tomography

Histocitiosis de células de Langerhans en su presentación focalizada en órbita

Contact Info

Product

Resources

About