Local Recurrence in Women With Stage I Breast Cancer: Declining Rates Over Time in a Large, Population-Based Cohort

Canavan, Joycelin F.; Truong, Pauline T.; Smith, Sally; Lü, Linghong; Lesperance, Mary; Olivotto, Ivo A.

doi:10.1016/j.ijrobp.2013.10.001

Cited by 29 publications

(7 citation statements)

References 35 publications

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“…6). These low local recurrence rates after BCT are also reported by others [34]. This brings us to the limitations of older trials, as the present results are certainly different from the past ones.…”

Section: Discussioncontrasting

confidence: 47%

The changing landscape in radiotherapy for breast cancer: Lessons from long term follow-up in some European breast cancer trials

Bartelink¹

2016

Radiotherapy and Oncology

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This review describes the developments in the radiation treatment of breast cancer based on some randomized European trials during the past decades. It will focus on the relevance of long term follow-up in breast cancer patients, starting with the surprising and important change in treatment results during follow-up shown in a locally advanced breast cancer trial. Breast conserving therapy (BCT) in stage I and II breast cancer was explored and tested in a randomized trial to prove equivalence between BCT and mastectomy. The positive outcome led to trials in breast conserving therapy with lower doses and partial breast irradiation. Finally the need for finding genetic profiles for predicting treatment response will be addressed in a trial with preoperative partial breast irradiation.

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Section: Discussioncontrasting

confidence: 47%

The changing landscape in radiotherapy for breast cancer: Lessons from long term follow-up in some European breast cancer trials

Bartelink¹

2016

Radiotherapy and Oncology

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“…The advancement of adjuvant hormonal therapy has been postulated to these result. 4 Distant recurrence in this study was observed in 27.4% of the samples and based on the Kaplan Meier survival curve; we extrapolated that at 25 months, 50% of the patients developed recurrences. This is relatively higher than other Asian countries, e.g Filipino.…”

Section: Resultsmentioning

confidence: 85%

“…Screen-detected cancer has a more favourable outcome and less tumor recurrence. 4 However the detection of the symptoms less than 1 month has been significantly correlated with higher survival as compared to increasing duration of symptoms with 12% decrease in survival if presented after 1 year. 10 Tumor size was found to be a significant factor of recurrence as proven by previous studies.…”

Section: Resultsmentioning

confidence: 94%

Prevalence of Breast Cancer and its Associated Factors for Recurrence in Hospital Tengku Ampuan Afzan from 2008 to 2012

Mahno,

Muhammad Amjad,

Kasian

et al. 2022

imjm

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INTRODUCTION: Breast cancer is the commonest malignancy in Malaysian women. Cancer recurrence commonly seen in the first 2 years can be detrimental. Thus, identifying its prognostic factors is important. MATERIALS AND METHODS: We have retrospectively analyzed 179 women with breast cancer based on 5 years single center database with minimum follow up of 2 years. The demographic and clinico[1]pathological characteristics were determined using descriptive statistics. Survival was calculated based on Kaplan-Meier method. Multivariate analysis by Cox proportional hazards was performed to evaluate the potential factors affecting breast cancer recurrence. RESULTS: Mean follow up was 42 months, with mean age 52 years and 60.9% presented in Stage II disease. Overall recurrence was 41.9% with local recurrence 2.1%, regional recurrence 12.3% and distant recurrence 27.4%. 50% of our patients developed recurrence at 25 months. On univariate analysis, time to first presentation was significantly correlated with recurrence. In multivariate analysis, the tumor size, lymph node positivity and lympho-vascular invasion were independently associated with recurrence. Discussion: To date, local studies on prognostic factors in breast cancer recurrence remained sparse. Based on this study, factors associated with breast cancer recurrence identified and coincides with the previous evidence. Furthermore, this would provide evidence to improve the survival for patients with breast cancer in local settings. CONCLUSION: Further studies also need to be done on the non-compliant patients with advanced disease at presentation to determine factors towards their perception of surgical care in breast oncology.

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“…2 This is the result of advances in breast cancer screening, surgical techniques, pathologic work up and adjuvant local and systemic therapy that improved local control after breast conserving treatment. 1 Moreover, patients who have already been treated for a previous cancer undergo a close follow-up that allows detecting a very small tumor recurrence. Salvage mastectomy represents the standard local treatment strategy in the case of ipsilateral breast tumor recurrence.…”

Section: Discussionmentioning

confidence: 99%

“…Nevertheless, breast relapse may occur in a small proportion of patients. 1 A significantly greater risk of developing breast cancer (BC), compared to the general population, has been demonstrated in women treated with chest radiotherapy (RT) at a younger age for Hodgkin lymphoma (HD) or other neoplasms. 2 In all the clinical situations where radiotherapy was already delivered on site and a new irradiation may be strongly correlated with severe late effects, the standard approach is mastectomy alone that results in a loco-regional control rate up to 90%.…”

Section: Introductionmentioning

confidence: 99%

Adjuvant intraoperative radiotherapy for selected breast cancers in previously irradiated women: Evidence for excellent feasibility and favorable outcomes

Blandino

Guenzi

Belgioia

et al. 2017

Reports of Practical Oncology & Radiotherapy

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Local Recurrence in Women With Stage I Breast Cancer: Declining Rates Over Time in a Large, Population-Based Cohort

Cited by 29 publications

References 35 publications

The changing landscape in radiotherapy for breast cancer: Lessons from long term follow-up in some European breast cancer trials

The changing landscape in radiotherapy for breast cancer: Lessons from long term follow-up in some European breast cancer trials

Prevalence of Breast Cancer and its Associated Factors for Recurrence in Hospital Tengku Ampuan Afzan from 2008 to 2012

Adjuvant intraoperative radiotherapy for selected breast cancers in previously irradiated women: Evidence for excellent feasibility and favorable outcomes

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