Local recurrence after radical prostatectomy: Characteristics in size, location, and relationship to prostate-specific antigen and surgical margins

Connolly, John A.; Shinohara, Katsuto; Presti, Joseph C.; Carroll, Peter R.

doi:10.1016/s0090-4295(99)80421-x

Cited by 197 publications

(88 citation statements)

References 24 publications

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“…Contrary to the treatment of prostate cancer in the definitive setting, the target volume in the postoperative setting is not well‐defined. The most common sites of clinical failure are the peri‐anastomotic site, bladder neck, retrovesical space, and, rarely, the regional lymph nodes (21) . Similar to patients treated in the definitive setting, precision radiotherapy requires reducing daily uncertainties in order to ensure target coverage while minimizing radiation exposure to critical surrounding structures.…”

Section: Discussionmentioning

confidence: 99%

Target localization for post‐prostatectomy patients using CT and ultrasound image guidance

Paskalev

Feigenberg

Jacob

et al. 2005

J Applied Clin Med Phys

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We conducted a study comparing B‐mode acquisition and targeting (BAT) ultrasound alignments based on CT data in the postoperative setting. CT scans were obtained with a Primatom CT‐on‐rails on nine patients. Two CT scans were obtained each week, while setup error was minimized by BAT ultrasounds. For the first three patients, a direct comparison was performed. For the next six patients, a template based on the shifts from the week 1 CT during treatment was used for subsequent setup. Comparison of isocenter shifts between the BAT ultrasound and CT was made by the difference, absolute difference, and improvement (using CT alignments as the reference technique). A total of 90 image comparisons were made. The average interfraction motion was 3.2 mm in the lateral, 3.0 mm in the longitudinal, and 5.1 mm in the AP direction. The results suggest that the CT‐based ultrasound templates can improve the localization of the prostate bed when the initial displacements are greater than 4 mm. For initial displacements smaller than 4 mm, the technique neither improved nor worsened target localization. However, ultrasound alignments performed without the use of a template deteriorated patient positioning for two out of three patients, demonstrating that the use of a CT template was beneficial even at small initial displacements.PACS numbers: 87.53.‐j, 87.53.Kn, 87.53.Xd

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Section: Discussionmentioning

confidence: 99%

Target localization for post‐prostatectomy patients using CT and ultrasound image guidance

Paskalev

Feigenberg

Jacob

et al. 2005

J Applied Clin Med Phys

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show abstract

“…In this latter study, 32 the authors conclude that TRUS had a higher sensitivity than DRE, but a lower specificity. No difference in establishing local recurrence existed in respect of surgical margins status, although more patients with seminal vesicle involvement (36 vs 23%) and less patients with positive lymph nodes (8 vs 20%) had local recurrence.…”

Section: Postradical Prostatectomy Trus-guided Anastomotic Biopsy T Amentioning

confidence: 69%

“…Hypoechoic lesions were the commonest finding in TRUS in both studies, 11,32 while cancer detection rates in groups with a hypoechoic lesion, were 64 and 66%, respectively. In this latter study, 32 the authors conclude that TRUS had a higher sensitivity than DRE, but a lower specificity.…”

Section: Postradical Prostatectomy Trus-guided Anastomotic Biopsy T Amentioning

confidence: 75%

“…In a similar report by Connolly et al, 32 114 patients with an elevated PSA, and a negative bone scan, were examined by TRUS and TRUS-guided biopsy. The authors have also reported a similar rate of positive biopsy (54%) but nearly one-third of patients required more than one TRUS biopsy sessions to establish local recurrence.…”

Section: Anastomotic Trus-guided Biopsy Predicting Factorsmentioning

confidence: 99%

“…DRE's accuracy was different in that aspect (finding of recurrent tumour in 30% of cases with normal DRE, but in 78% of cases with abnormal DRE). In terms of histological outcome, several studies report a variety of histological findings, while the previous mentioned studies 11,19,32,33,[36][37][38][39][40] have identified recurrent adenocarcinoma of the prostate as the only evidence of local presence of prostate tissue (Table 1).…”

Section: Diagnostic Accuracy: Histological Outcomementioning

confidence: 99%

See 2 more Smart Citations

Postradical prostatectomy TRUS-guided anastomotic biopsy. Where do we stand today?

Anagnostou

Doumas

Remzi

et al. 2004

Prostate Cancer Prostatic Dis

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The issue of performing tissue sampling from the vesicourethral anastomotic area postradical prostatectomy (transrectal ultrasound-guided biopsy) after radical surgical treatment of local disease has failed, still remains controversial. We review a selection of articles that evaluate this procedure as well as newer diagnostic modalities and we discuss how this technique may have a position in our treatment dilemmas in cases with biochemical failure of undetermined origin.

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MRI-Guided Therapeutic Procedures in Recurrent Prostate Cancer

Woodrum

Kawashima

Gorny

et al. 2012

Interventional Magnetic Resonance Imaging

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Local recurrence after radical prostatectomy: Characteristics in size, location, and relationship to prostate-specific antigen and surgical margins

Cited by 197 publications

References 24 publications

Target localization for post‐prostatectomy patients using CT and ultrasound image guidance

Target localization for post‐prostatectomy patients using CT and ultrasound image guidance

Postradical prostatectomy TRUS-guided anastomotic biopsy. Where do we stand today?

MRI-Guided Therapeutic Procedures in Recurrent Prostate Cancer

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