Local Flow Patterns After Implantation of Bioresorbable Vascular Scaffold in Coronary Bifurcations　― Novel Findings by Computational Fluid Dynamics ―

Abstract

Neglecting BRS reconstruction leads to significantly lower SS and SS heterogeneity, which is most pronounced at side branch ostia. Thinner struts can marginally reduce SS heterogeneity.

The Evolution of Data Fusion Methodologies Developed to Reconstruct Coronary Artery Geometry From Intravascular Imaging and Coronary Angiography Data: A Comprehensive Review

“…Recent reports have highlighted the need to refine the methodologies for the reconstruction of vessel architecture especially in stented segments (75)(76)(77). Advanced methodologies have been presented lately (Figures 4, 6) that are able to separately reconstruct stent geometry and lumen surface and then fuse these models to generate a final lumen-stent object.…”

Effects of local hemodynamics and plaque characteristics on neointimal response following bioresorbable scaffolds implantation in coronary bifurcations

“…Nonetheless, all previous pioneer studies disregarded the potential role played by the stent structure, particularly when the structure is detached from the vessel wall as with malapposition or jailing struts. Currently compelling evidences have shown how critical stent structure influences flow dynamics [17]. The foreign material protruding into the lumen disturbs laminar flow, and induces flow separation and recirculation locally [18].…”

Advancements and Opportunities in Characterizing Patient-Specific Wall Shear Stress Imposed by Coronary Artery Stenting

“…Methods imposed for patient-specific inlet boundary conditions include velocity-encoded (VENC; i.e., phase-contrast) flow data from magnetic resonance imaging (PC-MRI). The patient-specific inlet flow rate can also be obtained from angiography [58]. When such data are not available, other approaches such as waveforms from the literature are sometimes made to approximate patient-specific conditions by scaling according to the body surface area.…”

“…Other approaches in the combination of conventional extravascular and high-resolution intravascular imaging data to reconstruct the stented flow domain are also presented with varying degrees of detail in the literature [70,[76][77][78][79]. Recently, Li and colleagues described their process using 3D angiography and OCT imaging, which was featured for diseased coronary artery data sets [80] as well as those obtained after bioresorbable vascular scaffold (BVS) implantation [58]. Their approach pays particular attention to the inclusion of side branches that are likely to impact the local flow field.…”