Local dermal application of a compound lidocaine cream in pain management of cancer wounds

Peng, Li; Zheng, Haiyan; Dai, Yi

doi:10.1590/1414-431x20198567

Cited by 11 publications

(6 citation statements)

References 14 publications

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“…Compound lidocaine cream contains lidocaine and procaine. Lidocaine is a short-acting local anesthetic with fast onset; procaine has a long duration of efficacy and is the drug with the longest duration of efficacy in local anesthetics [ 22 ]. Therefore, compound lidocaine cream has the characteristics of fast onset and long maintenance time.…”

Section: Discussionmentioning

confidence: 99%

Combined Application of Grid Body Surface Locator and Preemptive Analgesia in Daytime Vertebroplasty

Zhao

Xie³

et al. 2022

Computational and Mathematical Methods in Medicine

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Objective. To explore the clinical advantages of grid body surface locator combined with preemptive analgesia in the treatment of osteoporotic lumbar fractures in daytime vertebroplasty. Methods. A retrospective study was conducted on 120 patients who underwent lumbar vertebroplasty in the Department of Orthopedics of General Hospital of Northern Theater Command from January 2017 to January 2020. According to the preoperative planning and analgesic mode of treatment, they were divided into the daily operation experimental group and the traditional mode control group. Prone positioning of a patient under anesthetic is safe of ensuring optimum surgical access for many procedures, providing that the risks are fully understood. The general baseline data, intraoperative fluoroscopy times and operation time, bone cement injection volume, bone cement permeability, VAS score before operation, 1 day, and 3 months after operation, and the recovery of anterior vertebral height before and after operation were analyzed. Results. There was no statistically significant difference in the preoperative general data between the two groups. One day after operation, the VAS score of the experimental group was lower than that of the control group, but there was no difference after 3 months. The permeability of bone cement in the experimental group was lower than that in the control group, the height of anterior edge of injured vertebra was better than that in the control group, and the operation time was less than that in the control group. Conclusion. The daytime operation experimental group can significantly alleviate postoperative pain, increase the amount of bone cement injection, and reduce the permeability of bone cement through preoperative planning of puncture path and key puncture points, combined with advanced labor pain, but there is no significant difference in long-term pain relief.

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Section: Discussionmentioning

confidence: 99%

Combined Application of Grid Body Surface Locator and Preemptive Analgesia in Daytime Vertebroplasty

Zhao

Xie³

et al. 2022

Computational and Mathematical Methods in Medicine

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“…Compound lidocaine cream is made from the mixture of 2.5% lidocaine and 2.5% procaine. It belongs to the amide class of local anesthetics, which has the characteristics of strong penetrability and non‐irritant, and the local dosage is small and without adverse effect on the body 8 . It takes at least 45 minutes for compound lidocaine cream to produce anesthesia effect on the non‐destructive skin surface, and the analgesic effect can be maintained for 30 min after indwelling for 90 min 9 .…”

Section: Discussionmentioning

confidence: 99%

Roller microneedles transdermal delivery of compound lidocaine cream for enhancing the analgesic effect: A randomized self‐controlled trial

Hanlin

Wanyue

Zhang

et al. 2022

J of Cosmetic Dermatology

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Objective: The purpose of this article is to investigate whether the percutaneous delivery of compound lidocaine cream by roller microneedles can shorten the minimal effective onset time of anesthesia, enhance the intensity of anesthesia and prolong the analgesic time, so as to provide a theoretical basis for exploring a comfortable, safe and effective anesthesia method for photoelectric cosmetic surgery.

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“…Previous studies lacked a quantitative assessment of RD. In our study, RD was defined at W1 as follows: 1) patients still had dizziness or imbalance without positional vertigo or nystagmus, as determined by positional-evoked maneuvers; 2) VAS score for dizziness was greater than 1 point ( 21 ). Patients without RD were defined as Group A.…”

Section: Methodsmentioning

confidence: 99%

Clinical and cVEMP Evaluation Predict Short-Term Residual Dizziness After Successful Repositioning in Benign Paroxysmal Positional Vertigo

Jiang

Shen

et al. 2022

Front. Med.

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ObjectiveResidual dizziness (RD) is a frequent symptom with unknown pathogenesis, often complained about by the patients with benign paroxysmal positional vertigo (BPPV), even after a successful canalith repositioning procedure (CRP). This study aims to quantitatively evaluate the short-term RD severity and its risk factors in patients with BPPV after successful CRPs.MethodsIn total two hundred and twenty patients with BPPV after successful CRPs (W0) were prospectively followed up for 1 week (W1). Besides demographics and serial neuropsychological assessments (including dizziness handicap inventory-DHI, etc.), patients also received cervical/ocular vestibular evoked myogenic potential (c/oVEMP) evaluation. RD was defined as patients with dizziness or imbalance, dizziness visual analog scale (VAS) >1, and without positional vertigo or nystagmus at W1. Demographic, clinical, and VEMPs differences were compared among the three groups: patients with minor (dizziness VAS 1–3) and moderate-to-severe RD (dizziness VAS > 3) and without RD.ResultsThe total frequency of RD at W1 was 49.1% (n = 108), with 32.3% (n = 71) minor, and 16.8% (n = 37) moderate-to-severe RD. Logistic regression analyses revealed that RD was closely associated with DHI status (OR = 2.101, P = 0.008) at W0, this effect was not present for minor RD. In addition to DHI score > 30 (OR = 4.898, P < 0.001) at W0, bilateral cVEMP absence (OR = 4.099, P = 0.005) was also an independent influential factor of moderate-to-severe RD.ConclusionOur study highlights the importance of RD quantified evaluation. DHI score >30 and bilateral cVEMP absence could increase the risk of short-term moderate-to-severe RD.

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Local dermal application of a compound lidocaine cream in pain management of cancer wounds

Cited by 11 publications

References 14 publications

Combined Application of Grid Body Surface Locator and Preemptive Analgesia in Daytime Vertebroplasty

Combined Application of Grid Body Surface Locator and Preemptive Analgesia in Daytime Vertebroplasty

Roller microneedles transdermal delivery of compound lidocaine cream for enhancing the analgesic effect: A randomized self‐controlled trial

Clinical and cVEMP Evaluation Predict Short-Term Residual Dizziness After Successful Repositioning in Benign Paroxysmal Positional Vertigo

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