Local Complications of Radiation and Chemotherapy Treatment of Patients With Squamous Cell Carcinoma of the Mucosa of the Oral Cavity

Abstract

Question on comprehensive dental care to patients with squamous cell carcinoma (SCC) of the mucous membrane of the oral cavity (MMOC) showed the importance of a team approach of physicians of allied specializations, careful planning and consistent implementation of rehabilitation treatment stages of cancer. The implementation of preventive measures showed a reduced severity or absence of complications conducted by the primary treatment. The data about the important role of preoperative sanitation of the oral cavity are presented. There are described the pathogenesis of the most common complications and identified effective methods of prevention and treatment, as well as the mechanisms of action of different prevention methods. Characteristic signs of “radiation caries”, oral mucositis, dysgeusia, xerostomia, lockjaw chewing muscles, osteoradionecrosis, dysphagia and neurotoxic effects of chemotherapy drugs are marked. It is necessary to emphasize the considerable effect of such complications on quality of life of patients after treatment. This again proves a need for an integrated approach and participation in the work of the specialists of a number of related disciplines.