Local Administration of 1% Ubretid in the Handling of Glaucoma, Myasthenia Gravis and Esotropia

Long-Lasting Inhibitory Effects of Distigmine on Recombinant Human Acetylcholinesterase Activity

“…1). Distigmine is used clinically in some Asian and European countries, including Japan and Germany, [2][3][4][5][6][7][8] and the main clinical indication for distigmine is myasthenia gravis. 2,9) However, in Japan, distigmine has also been used for glaucoma 3) and an underactive bladder.…”

“…Distigmine is used clinically in some Asian and European countries, including Japan and Germany, [2][3][4][5][6][7][8] and the main clinical indication for distigmine is myasthenia gravis. 2,9) However, in Japan, distigmine has also been used for glaucoma 3) and an underactive bladder. [4][5][6][7][8] The effectiveness and usefulness of distigmine for underactive bladder treatment have been shown in many clinical studies.…”

Long-Lasting Inhibitory Effects of Distigmine on Recombinant Human Acetylcholinesterase Activity

“…1). Distigmine is used clinically in some Asian and European countries, including Japan and Germany, [2][3][4][5][6][7][8] and the main clinical indication for distigmine is myasthenia gravis. 2,9) However, in Japan, distigmine has also been used for glaucoma 3) and an underactive bladder.…”

“…Distigmine is used clinically in some Asian and European countries, including Japan and Germany, [2][3][4][5][6][7][8] and the main clinical indication for distigmine is myasthenia gravis. 2,9) However, in Japan, distigmine has also been used for glaucoma 3) and an underactive bladder. [4][5][6][7][8] The effectiveness and usefulness of distigmine for underactive bladder treatment have been shown in many clinical studies.…”

Effects of Distigmine on the Mechanical Activity of Urinary Bladder Smooth Muscle

“…It and other carbamate ChE inhibitors have been used to treat myasthenia gravis in Asia, the Middle East, and Europe. [2][3][4][5] Distigmine has also been used to treat glaucoma in Japan. [6][7][8] Distigmine has also been applied as a remedy for dysuria in Japan since its release there in 1968.…”

“…[2][3][4][5] Distigmine has also been used to treat glaucoma in Japan. [6][7][8] Distigmine has also been applied as a remedy for dysuria in Japan since its release there in 1968. It was reported that distigmine has a therapeutic effect on neurogenically underactive bladder caused by surgery, spinal cord injury, and chronic diseases such as diabetes.…”

Effects of Distigmine on Electrical Field Stimulation-Induced Contraction of Mouse Urinary Bladder Smooth Muscles

“…Distigmine bromide (distigmine) is a carbamate group reversible cholinesterase (ChE) inhibitor that was chemically synthetized by Schmid et al in the 1950s [1][2][3] . Although the primary clinical indication for distigmine is its involvement in the treatment of myasthenia gravis [4][5][6] , in Japan, it is also used to treat glaucoma [7][8][9][10] and underactive bladder [11][12][13][14][15][16][17] .…”

Long-Lasting Inhibitory Effects of Distigmine on Recombinant Human Acetylcholinesterase Activity

“…1). Distigmine is used clinically in some Asian and European countries, including Japan and Germany, [2][3][4][5][6][7][8] and the main clinical indication for distigmine is myasthenia gravis. 2,9) However, in Japan, distigmine has also been used for glaucoma 3) and an underactive bladder.…”

“…Distigmine is used clinically in some Asian and European countries, including Japan and Germany, [2][3][4][5][6][7][8] and the main clinical indication for distigmine is myasthenia gravis. 2,9) However, in Japan, distigmine has also been used for glaucoma 3) and an underactive bladder. [4][5][6][7][8] The effectiveness and usefulness of distigmine for underactive bladder treatment have been shown in many clinical studies.…”

Effects of Distigmine on the Mechanical Activity of Urinary Bladder Smooth Muscle

“…It and other carbamate ChE inhibitors have been used to treat myasthenia gravis in Asia, the Middle East, and Europe. [2][3][4][5] Distigmine has also been used to treat glaucoma in Japan. [6][7][8] Distigmine has also been applied as a remedy for dysuria in Japan since its release there in 1968.…”

“…[2][3][4][5] Distigmine has also been used to treat glaucoma in Japan. [6][7][8] Distigmine has also been applied as a remedy for dysuria in Japan since its release there in 1968. It was reported that distigmine has a therapeutic effect on neurogenically underactive bladder caused by surgery, spinal cord injury, and chronic diseases such as diabetes.…”

Effects of Distigmine on Electrical Field Stimulation-Induced Contraction of Mouse Urinary Bladder Smooth Muscles

“…Distigmine bromide (distigmine) is a carbamate group reversible cholinesterase (ChE) inhibitor that was chemically synthetized by Schmid et al in the 1950s [1][2][3] . Although the primary clinical indication for distigmine is its involvement in the treatment of myasthenia gravis [4][5][6] , in Japan, it is also used to treat glaucoma [7][8][9][10] and underactive bladder [11][12][13][14][15][16][17] .…”

Long-Lasting Inhibitory Effects of Distigmine on Recombinant Human Acetylcholinesterase Activity

“…1). Distigmine is used clinically in some Asian and European countries, including Japan and Germany, [2][3][4][5][6][7][8] and the main clinical indication for distigmine is myasthenia gravis. 2,9) However, in Japan, distigmine has also been used for glaucoma 3) and an underactive bladder.…”

“…Distigmine is used clinically in some Asian and European countries, including Japan and Germany, [2][3][4][5][6][7][8] and the main clinical indication for distigmine is myasthenia gravis. 2,9) However, in Japan, distigmine has also been used for glaucoma 3) and an underactive bladder. [4][5][6][7][8] The effectiveness and usefulness of distigmine for underactive bladder treatment have been shown in many clinical studies.…”

Effects of Distigmine on the Mechanical Activity of Urinary Bladder Smooth Muscle

“…It and other carbamate ChE inhibitors have been used to treat myasthenia gravis in Asia, the Middle East, and Europe. [2][3][4][5] Distigmine has also been used to treat glaucoma in Japan. [6][7][8] Distigmine has also been applied as a remedy for dysuria in Japan since its release there in 1968.…”

“…[2][3][4][5] Distigmine has also been used to treat glaucoma in Japan. [6][7][8] Distigmine has also been applied as a remedy for dysuria in Japan since its release there in 1968. It was reported that distigmine has a therapeutic effect on neurogenically underactive bladder caused by surgery, spinal cord injury, and chronic diseases such as diabetes.…”

Effects of Distigmine on Electrical Field Stimulation-Induced Contraction of Mouse Urinary Bladder Smooth Muscles

“…Distigmine bromide (distigmine) is a carbamate group reversible cholinesterase (ChE) inhibitor that was chemically synthetized by Schmid et al in the 1950s [1][2][3] . Although the primary clinical indication for distigmine is its involvement in the treatment of myasthenia gravis [4][5][6] , in Japan, it is also used to treat glaucoma [7][8][9][10] and underactive bladder [11][12][13][14][15][16][17] .…”