Local Action of Oils Containing Vitamin A

Rötth, A. de

doi:10.1001/archopht.1940.00870020073008

Cited by 8 publications

(2 citation statements)

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“…The bioactive nature of intact ECM has been the main reason for its use in regenerative applications. , The sources for intact ECM explored so far include the dermis of the skin, − the small intestinal submucosa (SIS), − the urinary bladder mucosa (UBM) and submucosa (UBS), − the pericardium, − the basement membrane and stroma of decellularized liver, , the decellularized tendon, − and the amniotic membrane. − Depending on the location, structure, and function of their source organs, the respective ECM are varied in structure and molecular composition . In an effort to identify an intact ECM with homogeneous structural and compositional properties, the cholecyst was chosen as a source.…”

Section: Introductionmentioning

confidence: 99%

Scaffold with a Natural Mesh-like Architecture: Isolation, Structural, and in Vitro Characterization

et al. 2007

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An intact extracellular matrix (ECM) with a mesh-like architecture has been identified in the peri-muscular sub-serosal connective tissue (PSCT) of cholecyst (gallbladder). The PSCT layer of cholecyst wall is isolated by mechanical delamination of other layers and decellularized with a treatment with peracetic acid and ethanol solution (PES) in water to obtain the final matrix, which is referred to as cholecyst-derived ECM (CEM). CEM is cross-linked with different concentrations of glutaraldehyde (GA) to demonstrate that the susceptibility of CEM to degradation can be controlled. Quantitative and qualitative macromolecular composition assessments revealed that collagen is the primary structural component of CEM. Elastin is also present. In addition, the ultra-structural studies on CEM reveal the presence of a three-dimensional fibrous mesh-like network structure with similar nanoscale architecture on both mucosal and serosal surfaces. In vitro cell culture studies show that CEM provides a supporting structure for the attachment and proliferation of murine fibroblasts (3T3) and human umbilical vein endothelial cells (HUVEC). CEM is also shown to support the attachment and differentiation of rat adrenal pheochromocytoma cells (PC12).

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Section: Introductionmentioning

confidence: 99%

Scaffold with a Natural Mesh-like Architecture: Isolation, Structural, and in Vitro Characterization

et al. 2007

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“…The amniotic membrane was first used for therapeutic purposes in 1910 by Davis for skin transplantation and for the eye by de Rotth in 1940 [76] as reported by Rahman et al [67]. Studies have shown that the amniotic membrane can be used to treat partial limbal stem cell deficiency without the need for limbal cells [77].…”

Section: Limbal Cell Carriersmentioning

confidence: 99%