Lobular capillary hemangioma in a patient with ankylosing spondylitis using adalimumab: an exuberant presentation

Silva, Thadeu Santos; Guimarães, Carlos Leonardo Martins; Xavier, Isabela Pimenta; Rêgo, Vitória Regina Pedreira de Almeida

doi:10.1016/j.abd.2019.02.004

Cited by 1 publication

(2 citation statements)

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“…3,4 Several factors are associated with its development, including insect bites, minor trauma, hormonal changes during pregnancy, or drug induction by the intake of medication. 4,5 However, the lesion sometimes evolves spontaneously. 6 The lesion itself is a capillary hemangioma of the lobular subtype, so treatment is often required because of the associated risk of ulceration and bleeding.…”

Section: Introductionmentioning

confidence: 99%

“…The etiology of this common condition remains unclear and is often considered an imbalance between angiogenesis enhancers and inhibitors in the form of a hyperproliferative vascular response to various stimuli 3,4 . Several factors are associated with its development, including insect bites, minor trauma, hormonal changes during pregnancy, or drug induction by the intake of medication 4,5 . However, the lesion sometimes evolves spontaneously 6…”

Section: Introductionmentioning

confidence: 99%

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Treatment of pyogenic granuloma in children with a 595 nm pulsed dye laser: A retrospective study of 212 patients

Dong

et al. 2022

Lasers Surg Med

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Background: Pyogenic granuloma (PG) is a common vascular neoplasm in children. Data on 595 nm pulsed dye lasers for the treatment of PG in children remain scarce. Objective: To summarize the clinical characteristics and to evaluate the effectiveness and safety of the 595 nm pulsed dye laser for the treatment of PG in children. Study Design: Retrospective case series. Methods: A retrospective study was performed on 212 patients treated for PG with a 595 nm pulsed dye laser. SPSS version 19.0 was used for statistical analysis.Results: Among all 212 patients treated, 208 showed complete resolution of the lesion, and 4 dropped out after one treatment due to bleeding. A single treatment was sufficient in 139 (66.8%) patients, while two or three treatments were sufficient in 69 (33.2%) patients. Male patients responded better than female patients (χ 2 = 7.603, p =0.006). Lesions in the nonorbital region responded better than those in the orbital region (χ 2 = 7.445, p =0.006). The size of the lesion affected the effectiveness, and lesions with smaller diameters (t = −5.776, p <0.01) and heights (t = −10.368, p <0.01) showed better results. Complications and Side Effects: Twelve patients (5.8%) were reported to have local complications and side effects, including edematous erythema, slight bleeding, hyperpigmentation, and hypopigmentation. The edematous erythema and slight bleeding disappeared gradually after several days. The localized pigment changes usually resolved spontaneously and disappeared completely after 6 months. Conclusions: Our experience confirmed the efficacy and safety of the 595 nm pulsed dye laser for the treatment of PG in children.

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