“…Loading profiles have also been directly measured on cohorts of individuals fitted with transfemoral bone-anchored prostheses during a rehabilitation program (e.g., static load bearing, use of walking aids), standardized activities (e.g., walking in a straight line and around a circle, ascending and descending stairs and ramps), and unscripted daily activities (e.g., open environment, fall) [4,[15][16][17]19,26,27,35,[38][39][40][41][42][43][44][45][46]. These studies characterized the prosthetic loading profile using a range of variables associated with spatio-temporal characteristics (e.g., cadence, duration of gait cycle (GC) and support and swing phases), loading boundaries (e.g., maximum and minimum magnitude), a series of points of interest or local extremum (e.g., onset and magnitude of points of inflection between loading rate) and impulse [35,[38][39][40]43,46,[48][49][50]. Extraction of these variables for a large number of steps usually generated during ecological recordings was facilitated by the semi-automated detection of gait events (e.g., heel contact (HC), toe-off (TO)) and points of interest using set loading thresholds, as well as extraction of maximum or minimum loading magnitude within a time window selected manually, respectively [26,27,[51][52][53].…”