LncRNASnhg3Aggravates Hepatic Steatosis via PPARγ Signaling
Xianghong Xie,
Mingyue Gao,
Wei Zhao
et al.
Abstract:LncRNAs are involved in modulating the individual risk and the severity of progression in metabolic dysfunction-associated fatty liver disease (MASLD), but their precise roles remain largely unknown. This study aimed to investigate the role of lncRNASnhg3in the development and progression of MASLD, along with the underlying mechanisms.In vitroandin vivoexperiments revealed thatSnhg3is involved in lipid metabolism and steatosis. The result showed thatSnhg3was significantly downregulated in the liver of high-fat… Show more
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