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Syntheses, characterization and biological studies of zinc(II), copper(II) and cobalt(II) complexes with Schiff base ligand derived from 2‐hydroxy‐1‐naphthaldehyde and selenomethionine

“…[7 -9] Schiff base ligands with sulfur and nitrogen donor atoms in their structures act as good chelating agents for metal ions. [10,11] Coordination of such compounds with metal ions, such as copper, nickel and iron, often enhance their biological activities, [12] as reported for pathogenic fungi. [13] Selenium is in the same column of the periodic table as sulfur and may substitute for sulfur in methionine to form selenomethionine.…”

Schiff bases: An emerging potent class of pharmaceuticals

“…It has been proposed that the cytotxicity and antitumoral activity of these compounds is related, at least in part, to the reaction of thiosemicarbazone. Iron (III) derivatives of pyridine-2-carbaldehyde thiosemicarbazone support the evidence of the reaction with thiols and subsequent formation of iron (II) species (Singh et al, 2000). However, up to date there are no crystal structures of iron (II) entities arisen from this process.…”

Synthesis of some transition metal complexes of novel 1-methylpyrazole-3-aldehyde-4-(2-pyridyl) thiosemicarbazone: Spectroscopic and in vitro biological activity studies

“…The chemistry of transition metal complexes of heterocyclic thiosemicarbazone ligands has been receiving considerable attention primarily because of their bioinorganic relevance [11,12]. There have been attempts [13] to determine structural correlation's between transition metal ion complexes of heterocyclic thiosemicarbazones and their wide spectrum of biological applications.…”