Living Donor Right Liver Lobes: Preoperative CT Volumetric Measurement for Calculation of Intraoperative Weight and Volume

Aj, Lemke; Brinkmann, Martin; Schott, Thomas; Niehues, Stefan M.; Settmacher, Utz; Neuhaus, P.; Félix, R.

doi:10.1148/radiol.2403042062

Cited by 99 publications

(119 citation statements)

References 29 publications

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“…Regression analysis showed a high correlation between CT volumetry and water displacement (r = 0.985), but CT volumetry was found to be 13% higher than water displacement volumetry (P < 0.0001): the only relevant factor leading to this difference seemed to be blood perfusion. For these reasons, some authors have proposed the use of conversion factors and formulas, which should standardize imaging volumetry, providing a more realistic evaluation of liver volume [45,46] . Tongyoo et al [47] , for example, proposed a formula that combined sonographic portal vein diameters measurement and CT liver volumetry, providing a precise donor screening for graft size adequacy.…”

Section: Imaging: Which Modality Should Be Chosen?mentioning

confidence: 99%

Liver volumetry: Is imaging reliable? Personal experience and review of the literature

D’Onofrio

Robertis

Demozzi

et al. 2014

WJR

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The amount of the future liver remnant volume is fundamental for hepato-biliary surgery, representing an important potential risk-factor for the development of post-hepatectomy liver failure. Despite this, there is no uniform consensus about the amount of hepatic parenchyma that can be safely resected, nor about the modality that should be chosen for this evaluation. The pre-operative evaluation of hepatic volume, along with a precise identification of vascular and biliar anatomy and variants, are therefore necessary to reduce surgical complications, especially for extensive resections. Some studies have tried to validate imaging methods [ultrasound, computed tomography (CT), magnetic resonance imaging] for the assessment of liver volume, but there is no clear evidence about the most accurate method for this evaluation. Furthermore, this volumetric evaluation seems to have a certain degree of error, tending to overestimate the actual hepatic volume, therefore some conversion factors, which should give a more reliable evaluation of liver volume, have been proposed. It is widespread among non-radiologists the use of independent software for an off-site volumetric analysis, performed on digital imaging and communications in medicine images with their own personal computer, but very few studies have provided a validation of these methods. Moreover, while the pre-transplantation volumetric assessment is fundamental, it remains unclear whether it should be routinely performed in all patients undergoing liver resection. In this editorial the role of imaging in the estimation of liver volume is discussed, providing a review of the most recent literature and a brief personal series of correlations between liver volumes and resection specimens' weight, in order to assess the precision of the volumetric CT evaluation.

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Section: Imaging: Which Modality Should Be Chosen?mentioning

confidence: 99%

Liver volumetry: Is imaging reliable? Personal experience and review of the literature

D’Onofrio

Robertis

Demozzi

et al. 2014

WJR

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“…Corresponding to this representation, the Helmholtz equation can be written in terms of |G * | and φ by with Δ denoting the 3D-Laplacian operator and material density ρ (assumed to be 1.1 g/cm 3 in the following [46]). u ' m (ω n ) and u '' m (ω n ) denote the real and imaginary part of u * m (r,ω n ), respectively, acquired at the vibration frequency ω n .…”

Section: Appendixmentioning

confidence: 99%

Patient-Activated Three-Dimensional Multifrequency Magnetic Resonance Elastography for High-Resolution Mechanical Imaging of the Liver and Spleen

Guo

Hirsch

Streitberger

et al. 2013

Fortschr Röntgenstr

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Purpose: To introduce a novel in-vivo three-dimensional multifrequency magnetic resonance elastography (3D-MMRE) method for high-resolution mechanical characterization of the liver and spleen. Materials and Methods: Ten healthy volunteers were examined by abdominal single-shot 3D-MMRE using a novel patient-activated trigger system with respiratory control. 10 contiguous slices with 2.5?mm cubic voxel resolution, 3 wave components, 8 time steps, and 2 averages were acquired at 7 mechanical excitation frequencies from 30 to 60?Hz. The total imaging time was approximately 15?min. For postprocessing, multifrequency dual elasto-visco (MDEV) inversion was used to calculate high-resolution mechanical parameter maps of the abdomen including the liver and spleen. Results: Two parameters maps were generated from each image slice to capture the magnitude and the phase angle of the complex shear modulus. Both parameters depicted the mechanical structures of the abdomen with unprecedented high spatial resolution. Spatially averaged group mean values of the liver and spleen are 1.27???0.17 kPa and 2.01???0.69 kPa, indicating a significantly higher asymptomatic stiffness of the spleen compared to the liver. Conclusion: Patient-activated respiratory-gated 3D-MMRE combined with MDEV inversion provides highly resolved mechanical maps of the liver and spleen that are superior to previous elastograms measured by abdominal MRE. Citation Format: ??Guo J, Hirsch S, Streitberger KJ et?al. Patient-Activated Three-Dimensional Multifrequency Magnetic Resonance Elastography for High-Resolution Mechanical Imaging of the Liver and Spleen. Fortschr R?ntgenstr 2014; 186: 260???266

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“…[7][8][9][10][11] In addition, CT volume measurements have been shown to be well-correlated with the values calculated by various numerical formulas for liver weight/volume combining parameters, such as body weight, height, and body surface area. 7,8,11 Thus, CT volumetry is widely used for estimating liver volume.…”

Section: Introductionmentioning

confidence: 79%

Untitled

Shim²,

Song³

et al. 2017

Exp Clin Transplant

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Objectives: Our objective was to assess the accuracy of computed tomography volumetry in estimating liver volume in steatotic patients. Materials and Methods: We divided 641 liver donors (mean age 27 years, 71% male) into 4 groups ac cording to the extent of steatosis on predonation biopsy: with < 5% comprising group 1, 5% to 9% comprising group 2, 10% to 19% comprising group 3, and ≥ 20% comprising group 4. Graft mass estimation error (%) was calculated as follows: [(computed tomographymeasured volume minus graft weight)/graft weight] × 100. We obtained estimation errors, intraclass correlation coefficients, and Pearson correlation coefficients across the groups. Results: Baseline alanine aminotransferase and gammaglutamyltranspeptidase values were signi ficantly correlated with extent of steatosis. Mean graft weight and computed tomography-measured volume were 725.9 g and 741.2 mL. Mean estimation errors were comparable (1.5% for group 1, 2.7% for group 2, 3.0% for group 3, and 3.9% for group 4; P = .77). In multivariate linear regression, estimation error was inversely correlated with high-density lipoprotein cholesterol (P = .008). Overall, there was an excellent agreement between measured volume and actual weight, with intraclass correlation coefficients over 0.85 and Pearson correlation coefficients over 0.70 in all groups (P < .001).Conclusions: Preoperative computed tomography volumetry is an accurate tool for estimating volume regardless of the extent of steatosis.

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Living Donor Right Liver Lobes: Preoperative CT Volumetric Measurement for Calculation of Intraoperative Weight and Volume

Abstract: By using two equations developed from the data obtained in this study, expected intraoperative weight and volume can properly be determined from CT volumetric measurements.

Cited by 99 publications

References 29 publications

Liver volumetry: Is imaging reliable? Personal experience and review of the literature

Liver volumetry: Is imaging reliable? Personal experience and review of the literature

Patient-Activated Three-Dimensional Multifrequency Magnetic Resonance Elastography for High-Resolution Mechanical Imaging of the Liver and Spleen

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