Living Cellular Construct for Increasing the Width of Keratinized Gingiva: Results From a Randomized, Within‐Patient, Controlled Trial

Abstract

The use of an LCC may provide a safe and effective therapy for augmenting the zone of keratinized gingiva.

Soft Tissue Grafting Around Teeth and Implants

“…84 Search of site-appropriate tissue in the oral cavity has included application of living cellular sheet (LCS) in oral soft tissue therapy as a free gingival graft. 85,86 LCS is an allogenic graft composed of cultured keratinocytes and fibroblasts in bovine collagen and has been used for more than 14 years to treat patients with cutaneous wounds. [87][88][89][90] (Fig.…”

Strategies for Oral Mucosal Repair by Engineering 3D Tissues with Pluripotent Stem Cells

“…37,38 Recently, 3D, skin-like tissues have been approved for clinical use in the treatment of periodontal disease. 39 Levenberg et al first established proof-ofconcept that ectodermal and mesenchymal cells differentiated from hESCs could assemble into tissues displaying in vivo-like features and could integrate into the host vasculature. 40 In addition, tissues that show fully-mature, functional skin upon engraftment to mice have been engineered from hESC-derived keratinocytes.…”

Aplicación de biomateriales de base biológica, moléculas bioactivas e ingeniería de tejidos en cirugía plástica periodontal: Una revisión

“…Mc Guire y col. (66) realizaron un estudio en 96 pacientes, los cuales recibieron en el mismo día tratamiento con IGL y en el lado contralateral Matriz Celular Viva (MCV-también denominado TCB). Se realizaron controles a la semana, 4 semanas, 3 meses y 6 meses.…”