Livin expression promotes keratinocyte release of inflammatory mediators in psoriasis
Delu Che,
Yazhuo Li,
Bing Hang
et al.
Abstract:BackgroundPsoriasis is a prevalent, long‐term skin condition characterized by inflammation. Keratinocytes (KCs) are important effector cells that release inflammatory factors and chemokines to promote the inflammatory cascade in psoriasis. However, the mechanisms underlying the activation of KCs in psoriasis remain unclear. Livin suppresses apoptotic proteins and directly affects the growth and spread of cancer cells. Livin expression reportedly increases significantly in lesions of patients with psoriasis; ho… Show more
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