Liver Ultrasound Attenuation

Gatos, Ilias; Drazinos, Petros; Yarmenitis, Spyros; Theotokas, Ioannis; Koskinas, John; Koullias, Emmanouil; Mitranou, Asimina; Manesis, Emmanuel; Zoumpoulis, P.S.

doi:10.1097/ruq.0000000000000605

Cited by 5 publications

(2 citation statements)

References 56 publications

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“…Two complementary lines of evidence support this assumption. First, lipid accumulation in other organs (e.g., hepatic steatosis) is now recognized to cause a very similar sonographic pattern 23 . Second, Fornander et al 8 using quantitative muscle MRI have shown recently that cDMD had increased fat fractions in the thigh and calf muscles relative to controls.…”

Section: Discussionmentioning

confidence: 99%

Quantitative ultrasonography reveals skeletal muscle abnormalities in carriers of DMD pathogenic variants

Loureiro,

de Brito,

Iwabe

et al. 2024

Muscle and Nerve

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Introduction/AimsCarriers of DMD pathogenic variants may become symptomatic and develop muscle‐related manifestations. Despite that, few studies have attempted to characterize changes in the muscles of these carriers using imaging tools, particularly muscle ultrasound (MUS). The aim of this study was to compare lower limb MUS findings in carriers of DMD pathogenic variants (cDMD) vs healthy controls.MethodsTwenty‐eight women (15 cDMD and 13 controls) underwent clinical evaluation and MUS. We collected information about muscle‐related symptoms and assessed muscle strength. MUS was performed by a single physician (blind to the genetic status of subjects). The following muscles were assessed: rectus femoris, sartorius, tibialis anterior, and medial gastrocnemius. For each site, we computed data on muscle thickness, cross‐sectional area, sound attenuation index, and elastography. Between‐group comparisons were assessed using nonparametric tests and p‐values <.05 were deemed significant.ResultsNone of the subjects had objective muscle weakness, but exercise intolerance/fatigue was reported by four cDMDs and only one control. Regarding MUS, sound attenuation indices were significantly higher among carriers for all muscles tested. Longitudinal and axial deep echo intensities for the rectus femoris and tibialis anterior were also higher in the cDMD group compared with controls. No significant between‐group differences were noted for elastography values, muscle area, or mean echo intensities.DiscussioncDMD have skeletal muscle abnormalities that can be detected using quantitative MUS. Further studies are needed to determine whether such abnormalities are related to muscle symptoms in these patients.

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Section: Discussionmentioning

confidence: 99%

Quantitative ultrasonography reveals skeletal muscle abnormalities in carriers of DMD pathogenic variants

Loureiro,

de Brito,

Iwabe

et al. 2024

Muscle and Nerve

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“…Therefore, there has been a significant effort in investigating and developing non-invasive alternatives for steatosis evaluation, specifically in MRI and ultrasound. Several studies have shown the potential of ultrasound attenuation index to detect hepatic steatosis [9][10][11]. Using a clinically approved linear probe, the same technique has yet to be fully explored.…”

Section: Introductionmentioning

confidence: 99%

Comparison of Ultrasound Attenuation Imaging Using a Linear versus a Conventional Convex Probe: A Volunteer Study

Hänni,

Ruby,

Paverd

et al. 2024

Diagnostics

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The study aimed to investigate the feasibility of attenuation imaging (ATI) measurements using a linear probe on healthy volunteers and compare measurements with the conventional convex probe. Attenuation imaging measurements of the liver tissue were taken using ultrasound with a convex and a linear probe in 33 volunteers by two examining doctors, and the measurements were repeated 4–5 weeks later by one of them. The ATI values for the linear probe were in the range of the values for the convex probe for both examiners. Measurements did not change significantly for 32 out of 33 volunteers after 4–5 weeks when using the linear probe. The size of the region of interest (ROI) only impacted the ATI values for the convex probe; it did not affect the values taken with the linear probe. Healthy volunteers were measured, and their attenuation values were compared to those from a convex probe, commonly used in steatosis evaluation. When both probes were positioned in the same liver area, they showed good agreement in attenuation values, though depth significantly affected the measurements, with both probes providing different values at different depths. The study’s results aligned with previous research using the same system. Operator A and B’s results were compared, demonstrating similar ranges of values for both probes. The linear probe has been demonstrated to allow for superficial measurements and attain ATI values in line with that of the convex probe in the liver.

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Comparison of Visual Transient Elastography, Vibration Controlled Transient Elastography, Shear Wave Elastography and Sound Touch Elastography in Chronic liver Disease assessment using liver biopsy as ‘Gold Standard’

Gatos

Yarmenitis²,

Theotokas³

et al. 2022

European Journal of Radiology

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Liver Ultrasound Attenuation

Cited by 5 publications

References 56 publications

Quantitative ultrasonography reveals skeletal muscle abnormalities in carriers of DMD pathogenic variants

Quantitative ultrasonography reveals skeletal muscle abnormalities in carriers of DMD pathogenic variants

Comparison of Ultrasound Attenuation Imaging Using a Linear versus a Conventional Convex Probe: A Volunteer Study

Comparison of Visual Transient Elastography, Vibration Controlled Transient Elastography, Shear Wave Elastography and Sound Touch Elastography in Chronic liver Disease assessment using liver biopsy as ‘Gold Standard’

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