“…Several methods of automatic segmentation of liver and lesion have been proposed, consisting of level set parameter [8], [9], fast fuzzy c-means and adaptive watershed [10], [11], fully convolutional networks (FCNs) [12]- [15], segnet [16], encoder-decoder structure [17]- [23]. The most popular encoder-decoder architecture is the U-Net model [24] that has been modified to implement a lot of applications on medical image segmentation such as ischemic stroke lesion [25], pancreas [26], [27], retina vessel [28], [29], prostate [30], colorectal tumor [31], and brain tumor [32], etc.…”