Liver transplantation with continued dual antiplatelet therapy

Spieker, H; Benckert, Christoph; Quante, Markus; Thelen, Armin; Gaebelein, Gereon; Kaisers, Udo X.; Jonas, Sven

doi:10.12659/aot.883231

Cited by 7 publications

(1 citation statement)

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“…The patient was transfused with two units of platelets preoperatively and received another unit during the surgery as well as six units of packed red blood cells and six units of fresh frozen plasma. After massive transfusion the patient's course was complicated by myoglobinuria [14]. The authors do not report any results of perioperative TEG or platelet mapping study, and they do not comment on the indications to the blood, platelets or fresh frozen plasma transfusion.…”

Section: Discussionmentioning

confidence: 99%

Management of a patient on dual antiplatelet therapy presented for living donor liver transplant

Moguilevitch¹,

Delphin²,

Widyn³

et al. 2013

CRCM

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We report a case of a patient who underwent Living Donor Liver Transplantation (LDLT) while being continued on his dual antiplatelet regimen of clopidigrel and aspirin perioperatively. The patient had two drug eluting stents for coronary artery disease placed eight months prior to surgery. Preoperative thromboelastography and platelet mapping showed normal clot formation. Based on these tests it was determined that preoperative platelet transfusion was not necessary. The surgery proceeded relatively uneventfully. The patient received 1 unit of packed red blood cells intraoperatively and continued on aspirin during the postoperative period with no evidence of bleeding or cardiac ischemia.

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Section: Discussionmentioning

confidence: 99%