Liver transplantation using a right liver lobe from a living donor

Boillot, Olivier; Dawahra, M; Mechet, Isabelle; Poncet, Gilles; Choucair, Antoine; Henry, Luc; Boucaud, Catherine; Sagnard, Pierre; Scoazec, Jean‐Yves

doi:10.1016/s0041-1345(01)02908-6

Cited by 34 publications

(13 citation statements)

References 6 publications

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“…There have been an estimated 12 to 13 donor deaths (at least 7 involving adult‐to‐adult donation, at least 3 adult‐to‐child donations, and 3 late donor deaths) (Table 14–29), for a donor mortality rate of the order of 12 to13 in 6,000, or 0.2% (including donors of [LLS], left or right lobes, and donors to both adult and child recipients). The 10 early donor deaths probably involved 5 right lobe donations, 1 left lobe, 1 LLS, and 3 unspecified graft types.…”

Section: Resultsmentioning

confidence: 99%

Living donor liver transplantation—Adult donor outcomes: A systematic review

et al. 2005

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The objective of this study was to evaluate the safety and efficacy of adult-to-adult living donor liver transplantation, specifically donor outcomes. A systematic review, with searches of the literature up to January 2004, was undertaken. Two hundred and fourteen studies provided information on donor outcomes. The majority of these were case series studies, although there were also studies comparing living donor liver transplantation with deceased donor liver transplantation. Both underreporting and duplicate reporting is likely to have occurred, and so caution is required in interpretation of these results. Overall reported donor mortality was 12 to 13 in about 6,000 procedures (0.2%) (117 studies). Mortality for right lobe donors to adult recipients is estimated to be 2 to 8 out of 3,800 (0.23 to 0.5%). The donor morbidity rate ranged from 0% to 100% with a median of 16% (131 studies). Biliary complications and infections were the most commonly reported donor morbidities. Nearly all donors had returned to normal function by 3 to 6 months (18 studies). In conclusion, there are small, but real, risks for living liver donors. Due to the short history of adult-to-adult living donor liver transplantation, the long-term risks for donors are unknown. Liver Transpl 12: 24 -30, 2006.

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Section: Resultsmentioning

confidence: 99%

Living donor liver transplantation—Adult donor outcomes: A systematic review

et al. 2005

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“…8 While the transplant community reckons that donor safety comes first, 9-11 the donor procedure in ALDLT has an estimated mortality of 0.5%. 12 Devastating complications of donors themselves undergoing salvage liver transplantation have also been reported. 13 Apart from these incidences, about 20% 14 and up to 67% of donors in one series 15 developed complications.…”

mentioning

confidence: 99%

Donor quality of life before and after adult-to-adult right liver live donor liver transplantation

Chan

Liu

et al. 2006

Liver Transpl

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Donor right hepatectomy for adult-to-adult live donor liver transplantation (ALDLT) is a major surgical operation for the benefit of the recipient. Justification of procedure mandates knowledge of the possible physical and psychological negative effects on the donor. We prospectively and longitudinally quantified donor quality of life using generic and condition-specific questionnaires up to 1 year. The generic questionnaires were the Karnofsky Performance Status scale and the Chinese (Hong Kong) version of the Medical Outcomes Study 36-Item Short-Form Survey, which measures 8 health concepts: 4 physical components and 4 mental components. Within 1 year, 30 consecutive donors were included. These 11 male and 19 female donors (36.7% and 63.3%, respectively) had a median age of 35 years (range, 21-56 years). There was no donor mortality or major complications. Donor quality-of-life worsening was most significant in the first 3 postoperative months, particularly among the physical components. The physical and mental components returned to the previous levels in 6 to 12 months' time, though the Karnofsky performance scores were slightly lower at 1 year (P ϭ 0.011). Twenty-six (86.7%) donors declared that they would donate again if there were such a need and it were technically possible. It was noticed that older donors were more likely to express unwillingness to donate again. In conclusion, the temporary worsening of donor quality of life substantiates ALDLT as an acceptable treatment modality. Liver Transpl 12: 1529-1536, 2006.

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“…Following successful reports from the first series of eight cases in 1997 [2], right-lobe LDLT has developed rapidly and has been adopted by many transplant programs around the world. Through careful selection of donors with safe profiles, right-lobe LDLT has been successfully achieving satisfactory recipient outcomes [3][4][5][6][7][8][9][10][11].…”

Section: Introductionmentioning

confidence: 99%

Technical Tips and Tricks for Living Donations

Chok

2014

Curr Transpl Rep

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Adult right-lobe living-donor liver transplantation is a technically demanding operation. Since it was conducted for the first time in 1996, its application has been expanding tremendously and it has become the mainstay at most Asian liver transplant centers. This is the result of its success rate for both donors and recipients and because it has helped alleviated the severe shortage of deceased-donor liver grafts. Improved understanding of the anatomy of the liver and advances in surgical techniques has dramatically reduced the complication rates. Recipients now can have excellent long-term survival, while the risks borne by the donors are acceptable. This article presents the surgical tips and tricks for donor right hepatectomy, the back-table procedure and recipient operation. The management of small-for-size liver grafts and methods of biliary reconstruction are also discussed.

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Liver transplantation using a right liver lobe from a living donor

Cited by 34 publications

References 6 publications

Living donor liver transplantation—Adult donor outcomes: A systematic review

Living donor liver transplantation—Adult donor outcomes: A systematic review

Donor quality of life before and after adult-to-adult right liver live donor liver transplantation

Technical Tips and Tricks for Living Donations

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