Liver Transplantation in Brazil

Bittencourt, Paulo Lisboa; Farias, Alberto Queiróz; Couto, Cláudia Alves

doi:10.1002/lt.24487

Cited by 46 publications

(44 citation statements)

References 11 publications

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“…After the adoption of the Milan Criteria, there was a significant improvement in post-transplant overall survival of patients with HCC, reaching 75% in five years, with tumor recurrence rates ranging from 8%-20% (136,(155)(156)(157) . HCC represents one of the main indications for LT in Brazil nowadays and worldwide, accounting for 15%-50% of transplants performed in most centers (158)(159)(160)(161) .…”

Section: Liver Transplantationmentioning

confidence: 99%

Brazilian Society of Hepatology Updated Recommendations for Diagnosis and Treatment of Hepatocellular Carcinoma

Chagas

Mattos

Carrilho

et al. 2020

Arq. Gastroenterol.

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Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related mortality worldwide. The Brazilian Society of Hepatology (SBH) published in 2015 its first recommendations about the management of HCC. Since then, new data have emerged in the literature, prompting the governing board of SBH to sponsor a single-topic meeting in August 2018 in São Paulo. All the invited experts were asked to make a systematic review of the literature reviewing the management of HCC in subjects with cirrhosis. After the meeting, all panelists gathered together for the discussion of the topics and the elaboration of updated recommendations. The text was subsequently submitted for suggestions and approval of all members of the Brazilian Society of Hepatology through its homepage. The present manuscript is the final version of the reviewed manuscript containing the recommendations of SBH.

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Section: Liver Transplantationmentioning

confidence: 99%

Brazilian Society of Hepatology Updated Recommendations for Diagnosis and Treatment of Hepatocellular Carcinoma

Chagas

Mattos

Carrilho

et al. 2020

Arq. Gastroenterol.

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“…Among the possible bile complications, bile duct stenosis is the most common, representing 40% of all of them [2,3]. In Brazil, it occurred in São Paulo in 1985 and, currently, the country is third in the world in absolute number of transplants, after the United States and China [4][5][6].…”

Section: Introductionmentioning

confidence: 99%

Epidemiologic Study on the Incidence of Biliary Complications after Liver Transplantation

Silva¹,

Andrade²,

Lisboa³

et al. 2018

J Liver

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Introduction: Biliary complications after hepatic transplantation have a variable incidence of 10 to 25% among all complications after hepatic transplantation and mortality reported up to 10%, have an important impact on the patient's quality of life, since it implies the need for hospitalizations and multiple interventions for treatment. They are more frequent in the first year after transplantation, with progressive reduction of the frequency after 1 year. Objective: To evaluate the risk factors of greater impact in the development of bile duct stenosis in patients after liver transplantation. Methods: One hundred and eighty-eight charts of liver transplant patients were retrospectively evaluated. Inclusion criteria: liver transplanted patients from 2011 to December 2017. Exclusion criteria: deaths that occurred between the first month after transplantation, incomplete medical records and most cases of retransplants, except for patients who retransplanted as a consequence of their own complication. Results: Biliary complications were present in 14% (N=26) of the patients. Of these, 52% (N=21) presented stenosis of the biliary tract, followed by other complications such as cholangitis (20%), fistula calculation (10%), bilioma (3%). Among patients with bile duct stenosis, 19% (N=4) presented non-anastomotic stenosis and 81% (N=17) anastomotic stenosis. The cause of hepatopathy was in 42% of patients (N=9) ethanolic, followed by other causes such as: viral hepatitis, cryptogenic, autoimmune, fulminant hepatitis, NASH, CEP, glycogenosis and 1 case of secondary retransplantation to the bile complication itself. Conclusion: The incidence of biliary complications is comparable with the incidence reported in other institutions. The low incidence of bile duct stenosis reduces the power of the study to identify the most impacting risk factors.

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“…No Brasil, cerca de 10% dos transplantes hepáticos são por CHC (38) , a incidência anual é de 2,9%, cumulativa em 5 anos de 14,3% e sobrevida de 50% em 5 anos (39) . (39) .…”

Section: Figura 1 -Resposta Adaptativa Da Resistência Insulínica (Riunclassified

Efeito do sorafenibe na carcinogênese hepática experimental secundária à doença hepática gordurosa não alcoólica

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Liver Transplantation in Brazil

Cited by 46 publications

References 11 publications

Brazilian Society of Hepatology Updated Recommendations for Diagnosis and Treatment of Hepatocellular Carcinoma

Brazilian Society of Hepatology Updated Recommendations for Diagnosis and Treatment of Hepatocellular Carcinoma

Epidemiologic Study on the Incidence of Biliary Complications after Liver Transplantation

Efeito do sorafenibe na carcinogênese hepática experimental secundária à doença hepática gordurosa não alcoólica

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