Liver Transplantation for Decompensated Cirrhosis After Jejunoileal Bypass

Js, Markowitz; Seu, Philip; Ja, Goss; Yersiz, Hasan; Jf, Markmann; Dg, Farmer; Rm, Ghobrial; Li, Goldstein; Martin, Paul L.; Stribling, Risë; Rw, Busuttil

doi:10.1097/00007890-199802270-00019

Cited by 18 publications

(9 citation statements)

References 7 publications

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“…Performing bariatric procedures prior to transplantation would be a possible strategy to cope with this emerging problem (23, 24). However, one must consider other side‐effects of bariatric surgery, such as development of non‐alcoholic steatohepatitis (NASH) and even cirrhosis of the liver (25, 26). In addition, changes in the absorption of immunosuppressive agents have been outlined in several publications (27–29).…”

Section: Discussionmentioning

confidence: 99%

Laparoscopic gastric banding in a kidney–pancreas transplant recipient with new onset type II diabetes mellitus associated with morbid obesity

Bonatti

Schmitt

Northup

et al. 2008

Clinical Transplantation

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Combined kidney-pancreas transplantation is the treatment of choice for end-stage diabetic nephropathy. Post-transplant weight gain increases the risk for post-transplant complications and death owing to cardiovascular events. Gastric banding is an established treatment for moderate morbid obesity. We report on a patient who experienced significant weight gain and developed type II diabetes mellitus following successful kidney-pancreas transplantation. He underwent laparoscopic gastric banding and initially had good weight loss. However, lack of compliance with dietary guidelines led to transient failure of weight loss therapy. With further adjustment of the gastric band good weight loss was achieved.

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Section: Discussionmentioning

confidence: 99%

Laparoscopic gastric banding in a kidney–pancreas transplant recipient with new onset type II diabetes mellitus associated with morbid obesity

Bonatti

Schmitt

Northup

et al. 2008

Clinical Transplantation

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“…Bariatric surgery may rarely lead to liver failure, especially after jejuno-ileal bypass and biliopancreatic diversion. Protein malnutrition and bacterial overgrowth are the main causes of liver damage following bariatric surgery (44). A recent systematic review analyzed 14 studies reporting 36 patients listed to LT after bariatric surgery.…”

Section: Lt In Bariatric Surgerymentioning

confidence: 99%

Liver transplantation for rare liver diseases and rare indications for liver transplant

Finotti

Auricchio

Vitale

et al. 2021

Transl Gastroenterol Hepatol

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Liver transplantation (LT) is currently considered the gold standard treatment for end-stage liver failure. Compared to the first decades of its use, LT is associated with lower comorbidity and mortality, with a 5-year survival over 70%. Worldwide, liver cirrhosis and hepatocellular carcinoma represent the major indications to LT. However, almost 1% of LT is performed for rare diseases or rare indications, which include non-hepatocellular malignancy, vascular disorders, metabolic and congenital liver disorders. These diseases can lead to hepatocellular necrosis, biliary tree abnormality and/or hepatomegaly. Most of these diseases are not associated with liver failure but in highly selected patients, LT represent an effective therapy improving the overall survival and quality of life. Rare indications for LT often overlap with rare diseases. However, rare LT indications for non-rare diseases are rising in the last decades, especially for benign primary liver tumor, colon rectal liver metastasis, neuroendocrine liver metastasis, and cholangiocarcinoma (CCA). Non-rare diseases with rare indication for LT and rare adult disease with an indication for LT are categorized and discussed in detail, focusing on some disorders for which the literature provides a more definitive evidence base. Early referral to a transplant center is encouraged to provide an effective therapeutic option in these non-standard indications for LT.

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“…Historically BS procedures with a marked malabsorptive component, such as jejunoileal bypass (JIB) or BPD (Scopinaro procedure) were proven to cause severe life-threatening complications including acute liver failure in up to 10% of patient, and were therefore subsequently abandoned. 30 31 In a nationwide Belgian survey in 2010, 10 patients (nine of them with BPD and one JIB) were listed for LT due to severe liver failure after BS, with a median time of 5 years after the weight-loss surgical procedure. The authors concluded that, although rare, the BPD operation carries a potential risk of life-threatening liver failure.…”

Section: Progression Of Liver Fibrosis After Bs and Feasibility And Safety Of Bs In Patients With Cirrhosismentioning

confidence: 99%

Risks and Rewards of Bariatric Surgery in Advanced Chronic Liver Diseases

et al. 2021

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The burden of obesity and metabolic syndrome has determined a sharp increase in bariatric surgery (BS) procedures, which lead to marked weight loss, improved metabolic syndrome, reduced cardiovascular risk, and even improvement in nonalcoholic steatohepatitis (NASH). Despite these promising results, BS in patients with chronic liver disease can rarely lead to worsening of liver function, progression to cirrhosis and its complications, and even liver transplantation. On the other hand, since obesity in patients with cirrhosis is a major cofactor for progression to a decompensated stage of the disease and a risk factor for hepatocellular carcinoma, BS has been used to achieve weight loss in this population. In this review, we critically analyze the existing data on outcomes of BS in patients with cirrhosis and the possible mechanisms leading to fibrosis progression and worsening liver function in patients undergoing BS. Finally, we propose a set of measures that could be taken to improve the multidisciplinary management of liver disease in patients undergoing BS, including early recognition of malnutrition and alcohol misuse.

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Liver Transplantation for Decompensated Cirrhosis After Jejunoileal Bypass

Cited by 18 publications

References 7 publications

Laparoscopic gastric banding in a kidney–pancreas transplant recipient with new onset type II diabetes mellitus associated with morbid obesity

Laparoscopic gastric banding in a kidney–pancreas transplant recipient with new onset type II diabetes mellitus associated with morbid obesity

Liver transplantation for rare liver diseases and rare indications for liver transplant

Risks and Rewards of Bariatric Surgery in Advanced Chronic Liver Diseases

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