2024
DOI: 10.1111/liv.15894
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Liver transplantation and primary liver cancer in porphyria

Mattias Lissing,
Bruce Wang,
Staffan Wahlin

Abstract: The porphyrias are a heterogeneous group of metabolic disorders that result from defects in heme synthesis. The metabolic defects are present in all cells, but symptoms are mainly cutaneous or related to neuropathy. The porphyrias are highly relevant to hepatologists since patients can present with symptoms and complications that require liver transplantation (LT), and some porphyrias are associated with a high risk for primary liver cancer (PLC). Among the cutaneous porphyrias, erythropoietic protoporphyria (… Show more

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