Liver transplant scene in india

Soin, AS; Thiagarajan, Shivakumar

doi:10.4103/2394-7438.174841

Cited by 14 publications

(7 citation statements)

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“…Hepatitis C is the most common etiology, and living donor transplantation is the predominant method of transplantation [7, 11]. Since successful transplant activity began 18 years ago in this region, with almost 8000 transplants performed to date, it is imperative to demonstrate transplant outcomes for better understanding the therapeutic impact of liver transplantation in this region [5]. The current study was performed to determine patient survival in patients with end‐stage liver disease (ESLD) who underwent LDLT in the largest liver transplant center in Pakistan.…”

Section: Introductionmentioning

confidence: 99%

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Living Donor Liver Transplantation in South Asia: Single Center Experience on Intermediate‐Term Outcomes

et al. 2017

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Section: Introductionmentioning

confidence: 99%

“…With regard to liver transplantation, India and Pakistan have indigenous liver transplant programs. At present, there is an approximate need of 25,000 transplants per year in India but only 1400 transplants were performed in the year 2014 [5]. It is estimated that more than 1 million people in Pakistan need a liver transplant [1].…”

Section: Introductionmentioning

confidence: 99%

Living Donor Liver Transplantation in South Asia: Single Center Experience on Intermediate‐Term Outcomes

et al. 2017

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“…PMN (polymorphonuclear neutrophils) was measured amongst the study population. Patients who had PMN >250 cells/mm 3 were treated with cefotaxime in about 67% of cases and with amoxicillin+clauvulonic acid up to 29% remaining were on cefriaxone. (Table 4) Among 120 prescriptions, antimicrobials prescribed were 95%, 2.5 % were antivirals and 1% was antifungals ( Table 5).…”

Section: Resultsmentioning

confidence: 99%

“…At present the need for liver transplantation in India is estimated to be around 20/million population. The current rate of liver transplantation in India is around 1.2/million population 3 . Hepatocellular carcinoma (HCC), is the second most common cause of death due to malignancy in the world .…”

Section: Introductionmentioning

confidence: 99%

“…Although alcoholism is associated with more than 60 diseases, most mortality from alcoholism results from alcoholic liver disease (ALD). 3 ALD includes alcoholic steatosis, alcoholic hepatitis, and alcoholic cirrhosis, in order of increasing severity ALD accounts for 40% of mortality from cirrhosis. Annual mortality for ALD is 4.4/1,00,000 in the general population.…”

Section: Introductionmentioning

confidence: 99%

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Study on Prescribing Patterns of Antimicrobial Agents In Liver Disease Patients

Priya

Kumar

Raj

et al. 2022

Int J Life Sci Pharm Res

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The present study aims at analyzing the prescribing patterns of antimicrobial agents in different liver diseases and to identify the drug-drug interactions among the prescribed drugs. A cross sectional observational study was conducted from February to July 2018. A total of 120 cases of patients receiving antimicrobials having different types of liver diseases were included. Statistical analysis shows that 80% of the popuation were male and 64% of the population was above the age of 50 years.. Liver disease like Liver Cirrhosis, Non alcoholic steato hepatitis, Viral hepatits, Jaundice, Hepatocellular carcinoma was found to be present among the study population, 50% of the population was overweight and 32% were alcoholic. Majority of them had ascites, abdominal distention and pedal edema as chief complaints and complications were hepatic encephalopathy and esophageal varices. The prescribed antimicrobial agents were antibiotics (95%) viz., Piptaz, rifaximin and taxim. antivirals (4%) such as entecavir and antifungals (1%) likeflucanazole. The drugs were prescribed according to the guidelines of the hospital. Mostly broad spectrum antibiotics were used in the management of liver disorders like Linezolid, Meropenem, Ertapenem, and Tobramycin. In severe cases combination of antimicrobials were given for effective therapy. Patient's transplantation was based on the MELD score, as the MELD score increases, the mortality rate also increases. MELD score =40 indicates mortality rate is >70%.

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Leishmania donovani and Pneumocystis jirovecii (carinii) diagnosed on bronchoalveolar lavage cytology in a liver transplant recipient with Cytomegalovirus infection

Thakur

Sarin

Dhampalwar

et al. 2019

Diagnostic Cytopathology

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Liver transplant recipients are prone to several infections, including lung infections, which can lead to substantial morbidity and mortality. Bronchoalveolar lavage (BAL) cytology is a rapid and sensitive diagnostic tool to identify the etiologic agents. We report a rare case of a 24-year-old male, post Live donor liver transplantation for autoimmune chronic liver disease, who presented with cough, fever, weight loss, and cavitatory lesion in lung. BAL cytology revealed Leishmania donovani (LD) andPneumocystis jirovecii/carinii (PCP). Cytomegalovirus deoxyribonucleic acid polymerase chain reaction (CMV DNA PCR) test showed markedly raised levels. Patient was put on treatment for these multiple infections and showed significant improvement.Thus, rapid diagnosis of infections through BAL cytology is crucial in transplant recipients to institute timely therapy and avoid undesirable empirical treatments. Moreover, this case highlights a rare finding of LD bodies along with PCP in BAL cytology. K E Y W O R D SBAL cytology, bronchoalveolar lavage, Cytomegalovirus, Leishmania donovani, liver transplantation, Pneumocystis jirovecii (carinii)

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Liver transplant scene in india

Cited by 14 publications

References 0 publications

Living Donor Liver Transplantation in South Asia: Single Center Experience on Intermediate‐Term Outcomes

Living Donor Liver Transplantation in South Asia: Single Center Experience on Intermediate‐Term Outcomes

Study on Prescribing Patterns of Antimicrobial Agents In Liver Disease Patients

Leishmania donovani and Pneumocystis jirovecii (carinii) diagnosed on bronchoalveolar lavage cytology in a liver transplant recipient with Cytomegalovirus infection

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