Liver resection versus radiofrequency ablation in the treatment of cirrhotic patients with hepatocellular carcinoma

Parisi, Amilcare; Desiderio, Jacopo; Trastulli, Stefano; Castellani, Elisa; Pasquale, Rosario; Cirocchi, Roberto; Boselli, Carlo; Noya, Giuseppe

doi:10.1016/s1499-3872(13)60044-2

Cited by 12 publications

(14 citation statements)

References 41 publications

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“…One-and two-year survival was 80% and 65%, respectively. This finding agreed with Parisi et al [16] who concluded that surgical resection improved the overall survival and recurrence-free survival in comparison with RFA.…”

Section: Discussionsupporting

confidence: 92%

“…percutaneous ethanol injection, microwave, RFA, and brachytherapy) may be effective and feasible in the treatment of HCC patients who are not suitable for resection. [16] Among these, RFA may be beneficial to more patients than the others because of its large coagulated necrosis, fewer treatment sessions, and higher survival rates. [17][18][19][20] Rare studies have evaluated the results of treatment with RFA, by comparing it to liver resection.…”

Section: Discussionmentioning

confidence: 99%

“…There was no in-hospital mortality after RFA; the mean hospital stay ranged from 4 h to 24 h with a mean of 7 h. One-and two-year survival was respectively, 80% (16) and 65% (13).…”

Section: Group B: Percutaneous Radiofrequency Ablationmentioning

confidence: 95%

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Surgical resection or radiofrequency ablation in the management of hepatocellular carcinoma: Single center experience

Mansy¹,

Mohammed²,

Saber³

2015

Hepatoma Res

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Aim: The aim of this study is to prove or disprove the superiority of surgical resections over radiofrequency ablation (RFA) with respect to efficacy and safety. Methods: The study was conducted in Zagazig University Hospitals, which included 40 patients with hepatocellular carcinoma (HCC) during the period from November 2011 to December 2014, using either liver resection or RFA. Results: Hepatic resection was done in 20 patients (13 males, 7 females). Interventional RFA was done in 20 patients (12 males, 8 females). There was no in-hospital mortality after resection. One-and two-year survival rates were 85% and 70% respectively. There was no in-hospital mortality after RFA. One-and two-year survival rates were 80% and 65% respectively. Conclusion: Surgical resection is preferred over RFA in HCC-liver cirrhosis Child A patients with tumor sizes ≥ 3 cm. HCC-liver cirrhosis Child A patients with masses < 3 cm have almost the same results with both surgery and RFA. But in special cases such as central position lesions, RFA is preferred over resection. Also the decision for management may be changed according to patients well. Surgical resection 1-and 2-year survival rates were better than those treated with RFA.

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Section: Discussionsupporting

confidence: 92%

Section: Discussionmentioning

confidence: 99%

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Surgical resection or radiofrequency ablation in the management of hepatocellular carcinoma: Single center experience

Mansy¹,

Mohammed²,

Saber³

2015

Hepatoma Res

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“…Among the various local ablation techniques, radiofrequency ablation (RFA) has attracted the greatest interest and is the most commonly used treatment modality for small liver cancers in adults with preserved liver function reserve and for a variety of extra-hepatic sites, including the lung 6 and musculoskeletal system 7 . RFA has been reported to achieve a complete response comparable to the response obtained with surgical liver resection with a lower morbidity rate of 5–18% 8 9 10 and a lower mortality rate of 0–1.4% 10 11 12 . Percutaneous ethanol injection (PEI) is also an effective treatment that has been widely used in patients with small tumors.…”

mentioning

confidence: 88%

First Experience of Ultrasound-guided Percutaneous Ablation for Recurrent Hepatoblastoma after Liver Resection in Children

Liu

Zhou

Huang

et al. 2015

Sci Rep

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This study aimed to summarize the first experience with ultrasound-guided percutaneous ablation treatment (PAT) for recurrent hepatoblastoma (HB) after liver resection in children. From August 2013 to October 2014, PAT was used to treat 5 children with a total of 8 recurrent HB (mean size, 1.4 ± 0.8 cm; size range, 0.7–3.1 cm), including 4 patients with 7 tumors in the liver and 1 patient with 1 tumor in the lung. Technical success was achieved in all patients (5/5, 100%). The complete ablation rate after the first ablation session was 80% (4/5) on a patient-by-patient basis and 87.5% (7/8) on a tumor-by-tumor basis. Only 1 patient developed a fever with temperature >39 °C; it lasted 4 days after radiofrequency ablation (RFA) and was resolved by conservative therapy. During the follow-up period, new intrahepatic recurrences after PAT were detected in two patients. One died due to tumor progression 4 months after ablation. The median overall survival time after PAT was 13.8 months. PAT is a safe and promising therapy for children with recurrent HB after liver resection, and further investigation in large-scale randomized clinical trials is required to determine its role in the treatment of this disease.

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“…Recent retrospective studies from Japan and Italy evaluated SR and RFA in patients with small HCC and found similar results: Both studies showed similar OS rates but a higher recurrence rate for RFA [23][24][25][26]. LH may thus have advantages regarding tumor removal, while RFA may have advantage in relation to minimal invasiveness.…”

Section: Discussionmentioning

confidence: 83%

Laparoscopic hepatectomy versus radiofrequency ablation for minimally invasive treatment of single, small hepatocellular carcinomas

Song

Wang

et al. 2015

Surg Endosc

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Liver resection versus radiofrequency ablation in the treatment of cirrhotic patients with hepatocellular carcinoma

Cited by 12 publications

References 41 publications

Surgical resection or radiofrequency ablation in the management of hepatocellular carcinoma: Single center experience

Surgical resection or radiofrequency ablation in the management of hepatocellular carcinoma: Single center experience

First Experience of Ultrasound-guided Percutaneous Ablation for Recurrent Hepatoblastoma after Liver Resection in Children

Laparoscopic hepatectomy versus radiofrequency ablation for minimally invasive treatment of single, small hepatocellular carcinomas

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