Liver resection for extra-pancreatic biliary cancer: what is the role of laparoscopic approach?

Elmoghazy, Walid; Cowan, Jane; Tabchouri, Nicolas; Tinguely, Pascale; Bennamoun, Mostefa; Tubbax, Candice; Sarran, Anthony; Lefèvre, Marine; Lamer, Christian; Gayet, Brice; Fuks, David

doi:10.1007/s00464-019-06664-7

Cited by 11 publications

(34 citation statements)

References 26 publications

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“…For pCCA analysis, one comparative study (retrospective cohort) and nine noncomparative studies were included . Two records had data regarding both iCCA and pCCA …”

Section: Resultsmentioning

confidence: 99%

“…Regarding noncomparative studies, the intraoperative outcomes were investigated and are demonstrated in Figure , and shown in Table . Meta‐analysis of single proportions for noncomparative studies has shown estimated sizes of 0.49 for major liver resections (95% CI, 0.24‐0.74/heterogeneity I 2 36.53%, Figure A), 0.18 for overall (95% CI, 0.05‐0.34/heterogeneity I 2 = 0; Figure B) and 0.07 for major morbidities (95% CI, 0.03‐0.17; heterogeneity; likelihood ratio test χ 2 = 0; Figure C) and 0.03 for perioperative mortality (95% CI, 0.01‐0.11/heterogeneity; likelihood ratio test χ 2 = 0; Figure D).…”

Section: Resultsmentioning

confidence: 99%

“…Laparoscopic liver resections (LLR) are gaining wide acceptance among hepatobiliary surgeons in the last decades due to improvements in surgical technologies and operative techniques . The LLR generally is associated with lower operative blood loss, shorter postoperative hospital stay, and also lower complication rates when compared with open liver resections (OLR) . Initially, LLR was employed in the treatment of benign liver disease, and then its application extended to the treatment of both primary and metastatic liver tumors while maintaining oncological safety …”

Section: Introductionmentioning

confidence: 99%

“…However, the minimally invasive approaches to treat biliary tract tumors remain a challenge with fewer reports in the literature. Intrahepatic and perihilar cholangiocarcinomas often require major liver resections and formal hilar lymphadenectomy . Also, biliary tract or vascular reconstructions techniques may be needed, which markedly increases the procedure complexity .…”

Section: Introductionmentioning

confidence: 99%

“…Intrahepatic and perihilar cholangiocarcinomas often require major liver resections and formal hilar lymphadenectomy . Also, biliary tract or vascular reconstructions techniques may be needed, which markedly increases the procedure complexity . The aim of this systematic review is to evaluate short and long‐term outcomes of LLR for pCCA and iCCA.…”

Section: Introductionmentioning

confidence: 99%

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The role of minimally invasive hepatectomy for hilar and intrahepatic cholangiocarcinoma: A systematic review of the literature

Shiraiwa

Carvalho

Maeda

et al. 2020

Journal of Surgical Oncology

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Despite the fact laparoscopic liver resections (LLR) for cholangiocarcinoma is still limited, this systematic review addressed surgical and oncological outcomes of LLR to treat both perihilar cholangiocarcinoma (pCCA) and intrahepatic cholangiocarcinoma (iCCA). Five comparative and 20 noncomparative studies were found. Regarding iCCA, LLR had lower blood loss and less need for Pringle maneuver. However, open liver resections (OLR) were performed more for major hepatectomies, with better lymphadenectomy rates and higher number of harvested lymph nodes. High heterogeneity and selection bias were suggested for iCCA studies.

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“…For pCCA analysis, one comparative study (retrospective cohort) and nine noncomparative studies were included . Two records had data regarding both iCCA and pCCA …”

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

The role of minimally invasive hepatectomy for hilar and intrahepatic cholangiocarcinoma: A systematic review of the literature

Shiraiwa

Carvalho

Maeda

et al. 2020

Journal of Surgical Oncology

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A potential role for aspirin in the prevention and treatment of cholangiocarcinoma

Shen

2020

Intl Journal of Cancer

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Cholangiocarcinoma is the second most common primary hepatic cancer, with a rising incidence worldwide. Owing to late diagnosis and limited treatment options, the prognosis for cholangiocarcinoma remains dismal, compelling a search for new treatments. As aspirin exhibits a well‐supported chemopreventive effect on common cancers, researchers have proposed using aspirin as a potential preventive and adjuvant agent for cholangiocarcinoma. In the present review of the literature, we provide a background on cholangiocarcinoma and potential mechanisms of action underlying the anticancer effect of aspirin. Although the exact mode of action remains unclear, multiple downstream effects of aspirin may interfere with cholangiocarcinogenesis, tumour growth and metastasis—including inhibiting the COX‐2 pathway, preventing platelet aggregation and modulating certain proteins and signalling. This review also summarises evidence to support the chemopreventive effects of aspirin on common cancers, particularly colorectal cancer and discusses studies that report a positive outcome of aspirin in cholangiocarcinoma. Regular use of aspirin is associated with a reduced incidence of colorectal cancers as well as cholangiocarcinomas, and improved survival. Aspirin thus appears to play a role in the primary prevention and treatment of cholangiocarcinoma. However, further studies are needed to confirm these benefits and to establish a cause‐and‐effect relationship.

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Systematic review of perioperative and oncologic outcomes of minimally-invasive surgery for hilar cholangiocarcinoma

et al. 2021

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Liver resection for extra-pancreatic biliary cancer: what is the role of laparoscopic approach?

Cited by 11 publications

References 26 publications

The role of minimally invasive hepatectomy for hilar and intrahepatic cholangiocarcinoma: A systematic review of the literature

The role of minimally invasive hepatectomy for hilar and intrahepatic cholangiocarcinoma: A systematic review of the literature

A potential role for aspirin in the prevention and treatment of cholangiocarcinoma

Systematic review of perioperative and oncologic outcomes of minimally-invasive surgery for hilar cholangiocarcinoma

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