“…In hepatocytes exogenous albumin-bound fatty acids greatly stimulate triacylglycerol synthesis, but show smaller effects on phospholipid formation (Ontko, 1972;Sundler et at., 1974a), indicating the existence of metabolic control at this point. Several control points and mechanisms must be considered: (1) the activities and relative affinities for diacylglycerol of cholinephosphotransferase, ethanolaminephosphotransferase and diacylglycerol acyltransferase (Young &Lynen, 1969 ;Skurdal & Cornatzer, 1974;Fallon et al, 1975;Sribney et al, 1976;Kanoh & Ohno, 1976); (2) the influence on diacylglycerol utilization by its fatty acid structure (Hill et al, 1968;Kanoh, 1969;Akesson et al, 1970;D e KruyfT et al, 1970;Sundler et al, 1974a;Kanoh & Ohno, 1975 ;Fallon et al, 1976); (3) the effects on phosphotransferase activities by the concentrations of CDP bases (Sundler & Akesson, 19756) regulated ( 3 4 at the cytidylyltransferase steps (Fiscus & Schneider, 1966;Sundler & Akesson, 19756;Sundler, 1975), (36) at the kinase steps (Weinhold & Rethy, 1974) and/or (3c) by the supply of free bases (Sundler & Akesson, 19756).…”