Liver metastatic colonization by invasive cancer cells: a review of potential biomarkers with mitochondrial involvement
Daniel L. Pouliquen
Abstract:The liver, characterized by a unique metabolic and immunosuppressive environment, is also the organ to which invasive malignant cells of many different cancer types most frequently metastasize. The reasons for this organ-specific metastatic process have been investigated for decades. This review first provides an overview of recent breakthroughs in this field, introducing intercellular communication between circulating tumor cells and the heterogeneous cell populations of the liver, and modifications to the ex… Show more
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