Liver injury in coeliac disease – own study and review of the literature

Szaflarska-Popławska, Anna

doi:10.5114/pg.2011.24309

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2013

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“…The high predictive value of both positive and negative results of genetic tests (HLA-DQ2/DQ8) and their greater availability as well as non-invasive character and constantly falling price are arguments for performing genotyping in risk-group individuals such as first-degree relatives of celiac patients and patients with type 1 diabetes, autoimmune thyroiditis, autoimmune hepatitis, Down’s syndrome and Turner syndrome [ 11 ].…”

Section: Discussionmentioning

confidence: 99%

Family recognition of celiac disease

Szałowska

Bąk‐Romaniszyn

2013

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Celiac disease is a permanent intolerance to gluten that leads to small-bowel mucosal villous atrophy during autoimmune processes in genetically predisposed individuals. At present the diagnosis of celiac disease is based on characteristic clinical symptoms, the results of serological investigations (tissue transglutaminase ten times the upper limit of normal, presence of antiendomysial antibodies – EMA) and positive results of genetic examinations. The aim of this study is to present a medical history of a family in which the mother and younger son were diagnosed with celiac disease (confirmed by genotype examination). Before the genetic examination, the father and the elder son were also suspected of suffering from this disease (they were on gluten-free diets). The authors emphasize the usefulness of HLA-DQ2/DQ8 determination in first-degree relatives of celiac patients.

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Section: Discussionmentioning

confidence: 99%

Family recognition of celiac disease

Szałowska

Bąk‐Romaniszyn

2013

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Liver injury in coeliac disease – own study and review of the literature

Cited by 1 publication

References 30 publications

Family recognition of celiac disease

Family recognition of celiac disease

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