Liver infarct masquerading as intrahepatic cholangiocarcinoma

Fariduddin, Maria; Syed, Wajihuddin; Birjees, Ayesha; Naqvi, Muhammad Raza

doi:10.1080/08998280.2021.1930968

Cited by 1 publication

(1 citation statement)

References 14 publications

(12 reference statements)

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“…However, these effects were in the same direction with the adjusted OR = 3.06, 95% CI 2.29–4.09, and adjusted OR = 2.88, 95% CI 1.46–5.67 for both DBD and LM, respectively. Both DBD and LM are important indicators of CCA and can be detected through US screening according to previously reported studies 18 , 19 , 29 . Other studies have been conducted in the northeastern region of Thailand.…”

Section: Discussionmentioning

confidence: 82%

Associations between ultrasound screening findings and cholangiocarcinoma diagnosis in an at-risk population

Thinkhamrop

Khuntikeo

Chamadol

et al. 2022

Sci Rep

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The rate of cholangiocarcinoma (CCA) is increasing every year, especially in northeastern Thailand. Screening for CCA using ultrasonography (US) is the fastest technique to identify patients in early stage of CCA development. Currently, few studies have examined patterns of hepatobiliary abnormalities identified using US, which can be indicative of CCA. We aim to evaluate the rate of CCA and its relations to history of US findings. Our study included participants who underwent US and pathological diagnosis of CCA from the Cholangiocarcinoma Screening and Care Program, Northeast Thailand between 2013 and 2020. Data on histological findings were based on the standard protocol of the tertiary hospital at Khon Kaen University. CCA data is categorized into two groups (yes/no) to find the relationship with history of US findings. The adjusted odds ratio (AOR) and their 95% confidence intervals (CI) were used to evaluate the relationship obtained by multiple logistic regression. Of 1880 subjects who underwent US and a pathological diagnosis of CCA, the overall rate of CCA was 35.74%. CCA rate among those with liver mass (LM) was 54.85% and with dilated bile duct (DBD) was 62.01%. The relationship between DBD and CCA was highly significant (AOR = 3.46; 95% CI 2.74–4.36) followed by LM (AOR = 2.28; 95% CI 1.81–2.86) P value < 0.001. Our study reveals that US findings history have a strong association with CCA, especially in people diagnosed with DBD and LM. Therefore, these abnormalities can be indicators for suspected CCA diagnosis through US.

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Section: Discussionmentioning

confidence: 82%