Abstract:Background: Laparoscopic surgery is performed by the insufflation of gas like carbon di oxide (CO2) into the peritoneal cavity by artificial port which is called creating pneumoperitoneum. The CO2 pneumoperitoneum causes changes in the splanchnic microcirculation and can affect liver physiology. Although laparoscopic cholecystectomy offered many advantages over laparotomy, new concerns arose regarding the effects of CO2 pneumoperitoneum on liver function. Knowledge of the effects of CO2 pneumoperitoneum on liv… Show more
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