Liver function assessment by indocyanine green plasma disappearance rate in patients with intra-abdominal hypertension after “non-hepatic” abdominal surgery

Kovač, Nataša; Perić, Mladen

doi:10.1080/03007995.2018.1435522

Cited by 2 publications

(2 citation statements)

References 37 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Animal research confirmed that 15 mmHg carbon dioxide pneumoperitoneum caused more substantial hepatic injury (16). In the human study, the plasma disappearance rate (PDR) of indocyanine green (ICG), a compound marker for hepatosplanchnic perfusion, but not classic liver laboratory parameters, was positively correlated to intraabdominal pressure (17). In this retrospective study, with only the availability of laboratory tests of hepatic function, the results showed that under the same insufflation pressure (10 mmHg), some main parameters of hepatic function were changed in the postoperative, period which means pneumoperitoneum did affect the liver function.…”

Section: Discussionmentioning

confidence: 95%

Transperitoneal versus extraperitoneal robot-assisted laparoscopic radical prostatectomy on postoperative hepatic and renal function

Lee¹,

Tang²,

Li³

et al. 2020

Gland Surg

View full text Add to dashboard Cite

Background: In this retrospective study, we evaluated the effect of two approaches of robotic-assisted laparoscopic radical prostatectomy (RALP). The first approach was pneumoperitoneum via transperitoneal (TP-RALP), and the second approach was extraperitoneal (EP-RALP) on visceral function. We aimed to provide clinical evidence for the perioperative safety with RALP and to help the surgical team choose an appropriate approach for those with hepatic or renal insufficiency.Methods: One hundred and fifty-seven eligible prostate cancer patients from 2015 to 2019 were included in this study. The postoperative related laboratory tests were compared between transperitoneal and extraperitoneal. The primary endpoint was hepatic and renal function. We also evaluate the intraoperative amount of bleeding, the length of postoperative hospital stays, the occurrence of postoperative complications (lymphatic leakage, bleeding, and infection), and the prostate-specific antigen (PSA).Results: Postoperative total bilirubin and bound bilirubin in both groups were significantly increased, while total protein, albumin, globulin, urea, and uric acid were significantly decreased (P<0.05). The total protein, albumin, and globulin are significantly higher in the EP-RALP group than in the TP-RALP group (P<0.05) postoperatively. There are no statistical differences in estimated glomerular filtration rate (eGFR) and creatinine clearance (CCR) between these two groups, postoperatively.Conclusions: RALP had a significant effect on hepatic function after both TP-RALP and EP-RALP approaches, while the latter showed a lesser extent. Our results suggested that pneumoperitoneal pathways have significant effects on protein consumption. Thus, we should require a more cautious choice of surgical approaches when it comes to patients with impaired hepatic function or under risk of hepatic malfunction.

show abstract

Section: Discussionmentioning

confidence: 95%

Transperitoneal versus extraperitoneal robot-assisted laparoscopic radical prostatectomy on postoperative hepatic and renal function

Lee¹,

Tang²,

Li³

et al. 2020

Gland Surg

View full text Add to dashboard Cite

show abstract

“…Thanks to the unique physical characteristics of indocyanine green, determination of ICG elimination rate by pulse densitometry was first introduced in the late 1990s. While a large number of publications confirm a high correlation of invasive and non-invasive techniques, there are certain problems related to pulse densitometry [ 10 , 11 , 12 , 13 , 14 ]. In particular, impaired capillary blood flow [ 15 , 16 ], obesity, and tremor of the extremities prevent obtaining reliable data [ 14 ].…”

Section: Introductionmentioning

confidence: 99%

Design of Liver Functional Reserve Estimation Technique Based on Optical Densitometry

et al. 2020

View full text Add to dashboard Cite

This work is aimed at creating a modified invasive technique for assessing the liver’s functional reserves. A study of the degree of hepatodepression is carried out by measuring the plasma elimination of indocyanine green using the method of optical densitometry. This paper presents test results for an aqueous solution and an albumin solution, as well as the results of measurements of plasma elimination of indocyanine green for patients with liver disease. Perfecting the proposed method will make an important scientific contribution to modern diagnostic medicine. Diagnosing the stages in the progression of the disease and its developing complications can make it possible to rapidly correct the patient’s treatment algorithm, achieving positive outcomes in medical practice.

show abstract

Liver function assessment by indocyanine green plasma disappearance rate in patients with intra-abdominal hypertension after “non-hepatic” abdominal surgery

Abstract: The results suggest that PDR/ICG and ICG R15 are useful dynamic tests for evaluation of complex liver function and survival prediction after major abdominal surgery in patients with IAH.

Cited by 2 publications

References 37 publications

Transperitoneal versus extraperitoneal robot-assisted laparoscopic radical prostatectomy on postoperative hepatic and renal function

Transperitoneal versus extraperitoneal robot-assisted laparoscopic radical prostatectomy on postoperative hepatic and renal function

Design of Liver Functional Reserve Estimation Technique Based on Optical Densitometry

Contact Info

Product

Resources

About