Liver fibrosis evaluation by ARFI and APRI in chronic hepatitis C

Li, Sumei; Li, Guangxia; Fu, Dongmei; Yu, Wei; Dang, Li-Qun

doi:10.3748/wjg.v20.i28.9528

Cited by 33 publications

(36 citation statements)

References 30 publications

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“…To combine sensitivity, specificity, and AUROC, 21 articles with 22 studies and 2,691 patients were included in the diagnosis analysis. Of the 21 articles, 11 [15,18,20,22,[26][27][28][29][30]33,35] articles provided ARFI values that were combined in the analysis. Details are present in figure 1.…”

Section: Article Selectionmentioning

confidence: 99%

Acoustic Radiation Force Impulse (ARFI) Elastography for non‑invasive evaluation of hepatic fibrosis in chronic hepatitis B and C patients: a systematic review and meta-analysis

Qiu

Dong

et al. 2017

Med Ultrason

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Aim: The purpose of the study was to assess the effect of Acoustic Radiation Force Impulse (ARFI) elastography in the diagnosis of liver fibrosis in chronic hepatitis B and C patients through Meta-analysis. Material and methods: Four databases (PubMed, the Cochrane Library, WanFang data, and CNKI) were searched. The key words were: (“ARFI” or “acoustic radiation force impulse”) combined with “liver fibrosis” and (“chronic hepatitis” or “HBV HCV”). Heterogeneity (I2) was assessed, and its source was analyzed through meta-regression. Results: 21 articles with 2,691 patients were included. The compositeSe=0.79 (95% CI: 0.76-0.83) and Sp=0.86 (95% CI: 0.85-0.88). ARFI elastography showed a better ability to evaluate higherstage liver fibrosis and liver cirrhosis (F=3 and F=4, respectively). For F≥3, Se=0.84 (95% CI: 0.80-0.88, I2=61.37), Sp=0.90 (95% CI: 0.86-0.92, I2=65.10), and AUROC=0.94 (95% CI: 0.91-0.95). Se and Sp and AUROC of F=4 were 0.86 (95% CI: 0.80-0.91, I2=70.67), 0.84 (95% CI: 0.80–0.88, I2=78.94) and 0.91 (95% CI: 0.89-0.94), respectively. Besides, the combined RFI values indicate that CHC patients had higher ARFI values especially in the F3 stage (1.87 [95% CI: 1.67-2.06] and 2.31[95% CI: 2.09-2.52] for CHB and CHC, respectively). Conclusion: ARFI elastography is accurate and reliable in the diagnosis of CHB- and CHC-induced liver fibrosis and is especially suitable for the evaluation of stages F≥3 and F=4. CHC patients manifest higher ARFI values than CHB patients especially in the F3 stage.

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Section: Article Selectionmentioning

confidence: 99%

Acoustic Radiation Force Impulse (ARFI) Elastography for non‑invasive evaluation of hepatic fibrosis in chronic hepatitis B and C patients: a systematic review and meta-analysis

Qiu

Dong

et al. 2017

Med Ultrason

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“…In a previous issue of the World Journal of Gastroen terology, we have read the article by Li et al [1] with great interest. We would like to thank the authors for their comprehensive contribution.…”

Section: To the Editormentioning

confidence: 99%

“…However, it is our wish to make minor criticism over the present study from the perspective of methodology. First, the measurements of Acoustic Radiation Force Impulse Imaging were performed in the right liver lobe through the intercostal space in present study [1] . Uslu et al [2] demonstrated that subcostal approach to the liver parenchyma was significantly superior to intercostal approach for the evaluation of liver stiffness in their study.…”

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confidence: 99%

Non-invasive evaluation of liver fibrosis by acoustic radiation force impulse and aminotransferase:platelet ratio index in chronic hepatitis C

Karagöz¹

2016

WJH

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“…Aminotransferases are sensitive indicator of hepatocyte injury. The pattern of aminotransferase elevation, increasing AST/ALT ratio can be helpfull to diagnose in patients with chronic hepatitis [6], [7]. The ratio of serum AST/ALT was describe by De Ritis and known as De Ritis ratio.…”

Section: Introductionmentioning

confidence: 99%

Correlation Between Aspartate Aminotransferase/ Alanine Transferase Ratio (AST/ALT Ratio) and Stage of Liver Fibrosis in Patients with Chronic Hepatitis

Lumongga¹,

Anggraeni²

2017

Proceedings of the 1st Public Health International Conference (PHICo 2016)

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Abstract-Fibrosis is hallmark histologic event of chronic liver disease. Liver biopsy remains the gold standard for diagnosis and assessment of liver fibrosis in patients with chronic hepatitis. However, its invasive procedure and can have complication, not suitable for continous observation of liver fibrosis.The aspartate aminotransferase-alanin transferase ratio (AST/ALT ratio) has been used to evaluate prognosis of liver fibrosis and non-invasive proseduce for chronic hepatitis patients. To evaluate correlation betwen AST/ALT ratio and the stage of histologic liver fibrosis in chronic hepatitis patients.The study was restrospective design, where liver biopsy specimen has been collected from fourty chronic hepatitis patients during period Januari 2012 to December 2015. All histological slides were reviewed by two pathologists for evaluating histologic liver fibrosis by using Metavire score system. Patients characteristic were descriptifly analized, AST/ALT ratio and the stage of fibrosis were analized by using Spearman's correlation. The 40 patients were identified. The mean of age was 41 years, 70% patients were male. The number of patients with stage F1, F2, F3 and F4 of fibrosis respectively were 2 (5%), 16 (40%), 11 (27,5%), and 11(27,5%). The mean of AST/ALT ratio was 1,45 ± (SE mean 0,14) .We found that there was statistically significant positive correlation between AST/ALT ratio with the stage of fibrosis (r = 0,843 ; p value< 0,01). AST/ALT ratio was correlated with the stage of fibrosis. It is recomended to used the ratio as prediction of pogressive liver functional impairment.

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Liver fibrosis evaluation by ARFI and APRI in chronic hepatitis C

Abstract: Both ARFI and APRI could evaluate liver fibrosis stages in chronic hepatitis C. ARFI is more accurate than the APRI index.

Cited by 33 publications

References 30 publications

Acoustic Radiation Force Impulse (ARFI) Elastography for non‑invasive evaluation of hepatic fibrosis in chronic hepatitis B and C patients: a systematic review and meta-analysis

Acoustic Radiation Force Impulse (ARFI) Elastography for non‑invasive evaluation of hepatic fibrosis in chronic hepatitis B and C patients: a systematic review and meta-analysis

Non-invasive evaluation of liver fibrosis by acoustic radiation force impulse and aminotransferase:platelet ratio index in chronic hepatitis C

Correlation Between Aspartate Aminotransferase/ Alanine Transferase Ratio (AST/ALT Ratio) and Stage of Liver Fibrosis in Patients with Chronic Hepatitis

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