Liver enzyme profiles after initiating biological treatment in children with inflammatory bowel diseases
Laura Räisänen,
Anne Nikkonen,
Kaija‐Leena Kolho
Abstract:ObjectivesBiological treatments (BTs) are essential in managing pediatric inflammatory bowel diseases (PIBDs). Elevated liver enzymes sometimes succeed BT, yet elucidating studies are scarce. We addressed liver biochemistry after introducing BT and searched for their determinants.MethodsWe identified PIBD patients receiving infliximab, adalimumab, vedolizumab, or ustekinumab at the Children's Hospital, University of Helsinki, Finland, in 2000–2023, and followed their alanine transaminase (ALT) and γ‐glutamyl t… Show more
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